Tri A - Organelle Disease

Question 1

What condition affects the Cell Membrane?

Answer 1

Cystic Fibrosis

Question 2

Describe Cystic Fibrosis

Answer 2

Defect affecting chloride channels
Causes abnormal, thick mucus secretion in respiratory tract
Clogged pancreatic duct
Clogged respiratory tract

Question 3

What condition affects Lysosomes?

Answer 3

Tay-Sachs disease

Question 4

Describe Tay-Sachs Disease

Answer 4

Lysosomal enzymes are either absent or non functional
Material build up in brain
Brain cells swell - seizures, blindness

Question 5

What condition affects Peroxisomes?

Answer 5

Adrenoleukodystrophy (ALD)

Question 6

Describe Adrenoleukodystrophy (ALD)

Answer 6

Missing protein in Peroxisome membrane
Cannot transport essential enzyme
Cannot break down long chain fatty acids
Build up in brain

Question 7

What condition affects the Mitochondria?

Answer 7

Mitochondrial Disease

Question 8

Describe Mitochondrial Disease

Answer 8

Lower energy levels in cells
Can affect every system in the body
Systems don’t work correctly

Question 9

What condition affects Ribosomes?

Answer 9

Ribosomopathies

Question 10

Describe Ribosomopathies

Answer 10

Impaired function and formation of bone marrow
Poor formation of blood cells

Question 11

What condition affects the Golgi Complex?

Answer 11

Achondrogenesis

Question 12

Describe Achondrogenesis

Answer 12

Poor development of skeleton
Caused by genetic mutation
Alzheimer’s is link to disrupted Golgi Complex