Transmissions of Axons and Synapses Flashcards
Define Synaptic transmission
Integrating/processing of information
Define Axonal transmission
Transmitting information from A to B
What are the 5 fundamentals processes of neurotransmission?
1) Manufacture (Intracellular biochemical processes)
2) Storage (Vesicles)
3) Release (Action Potential)
4) Interaction with post-synaptic receptor
5) Inactivation
What are examples of fast neurotransmitters(2) and how long do they last?
Ach, GABA,
Short lasting
What are examples of neuromodulators(3) and how long do they last?
Dopamine, Serotonin, Noradrenaline
Long lasting
Role of an Endorphin?
Peptide with opiate-like effects, inhibiting the release of substance P
How long does the refractory period last?
And 2 main components
5-10ms
Absolute RP followed by the Relative RP
What is the neuronal resting potential?
-70mV
What is the relative refractory period?
Follows absolute RP, when a 2nd stimulus stronger than first needed to produce a successive AP
How is the neuronal RP maintained?
3Na+ pumped out for every 2K+ in (SOPI)
(Requires ATP and lots of Na+/K+ pumps_