Translation

Question 1

Amino acids attached to tRNA by what enzyme

Answer 1

aminoacyl tRNA synthase

Question 2

tRNA end with what sequence at 3’ end?

Answer 2

CCA

Question 3

aminoacyl tRNA synthase works at what end of tRNA?

Answer 3

3’ end

Question 4

Ribosomal subunits are synthesized where?

Answer 4

nucleus

Question 5

Eukaryotic ribosomal subunits? What unit do they form

Answer 5

60S and 40S –> 80S

Question 6

Prokaryotic ribosomal subunits? What unit do they form?

Answer 6

50S and 30S –> 70S

Question 7

23S ribosomal subunit is part of what?

Answer 7

50S (prokaryote)

Question 8

First tRNA binds at what site of 70S ribosome?

Answer 8

P site

subsequent tRNAs bind at A site

Question 9

Factor required for translocation?

Answer 9

Elongation factor G - prokaryotes

Elongation factor 2 - eukaryotes

Question 10

Antibiotic that binds to 30S prior to initiation preventing tRNA from binding

Answer 10

aminoglycosides

Question 11

Antibiotic that binds to 30S in preventing aminoacyl-tRNA from getting to A site

Answer 11

tetracyclines

Question 12

Antibiotic that binds to 50S preventing initation

Answer 12

linezolid

Question 13

Antibiotic that binds to 50S and inhibits peptidyltransferase

Answer 13

chloramphenicol (at 23S within 50S)

Question 14

Antibiotic that binds to 50S inhibiting translocation

Answer 14

mAcrOlide (trAnslOcate)
clindamycin (name similar to macrolides) and lincomycin
streptogramins

Question 15

Cells that make extracellular proteins

Answer 15

Fibroblasts
Hepatocytes
Plasma cells

Question 16

Fibroblasts make these extracellular proteins

Answer 16

Collagen, fibrillin, elastin