translation Flashcards

1
Q

number of codons that encode for 20 amino a.

A

64

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2
Q

initiation signal and codes for methionine

A

AUG

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3
Q

match amino a. to codons in mRNA

A

tRNA

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4
Q

pairs with the codon on mRNA

A

anticodon

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5
Q

term for several different codosn that can specifiy an amino acid

A

wobble base pairing

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6
Q

wobble location

A

thrid position

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7
Q

covalently couple the amino acid to its appropriate tRNA

A

aminoacyl-tRNA synthetases

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8
Q

proofreading steps fro aa-TRNA synthesis

A

selection, editing

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9
Q

process of amino a. binding to synthetase

A

activation

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10
Q

proteins synthesized in this order

A

N end to C end

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11
Q

Formation of peptide bond favorable because of this attachment

A

covalent attachment of tRNA

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12
Q

performs proteins synthesis using more than 50 proteins and several RNA molecules

A

ribosome

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13
Q

ribosome unit that matches tRNA to codon

A

small subunit

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14
Q

Ribosome unit that catalyzes peptide bond formation

A

large unit

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15
Q

Three tRNA binding sites

A

E (exit), P (peptide bond formation) and A (activating/entrance)

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16
Q

maximum number of binding sites occupied

17
Q

stages of translation

A

intiation, elongation, termination

18
Q

Protein finds the place to start protein synthesis

19
Q

loads the initiator tRNA on the small ribosomal unit

A

eukaryotic initiation factors

20
Q

the disassociation of this after the AUG start permit the large ribosomal unit to join

A

initiaition factors

21
Q

encode for several proteins

A

polycistronic

22
Q

start codon sequence for bacteria

A

Shine-Delgarno

23
Q

step one of elongation

A

tRNA bind amino a. to A site

24
Q

step two of elongation

A

peptide is released fromm tRNA in P site and binds to A site

25
step three of elongation
conformation changes move mRNA 3 nucleotides and reset ribosome to receive next tRNA
26
these factors assist in elongation process
Elongation Factors, EF-Tu and EF-G
27
3 stop codons
UAA, UAG, UGA
28
peptidyl transferase adds this molecule to tRNA at stop codon, breaking the chain
water
29
At termination, subunits do this
Separate
30
series of ribosomes that translate same eukaryotic mRNA molecule
polyribosome
31
protein synthesis occurs here in addition to ribosomes
Rought Endoplasmic Reticulum
32
inhibitors of protein synthesis are used as this drug
antibiotics