enyzmes and bioenergetics

Question 1

Phase 1 of respiration

Answer 1

oxidation of fuels

Question 2

Phase 2 of respiration

Answer 2

ATP generation from oxidative phosphorylation

Question 3

Activation Energy

Answer 3

delta G

Question 4

delta H < 0

Answer 4

exothermic

Question 5

delta H > 0

Answer 5

endothermic

Question 6

delta G (-)

Answer 6

spontaneously forward

Question 7

delta G (+)

Answer 7

Spontaneously reverse

Question 8

Decrease activation energy and increase rate of reaction

Answer 8

enzymes

Question 9

links the hydrolysis of ATP to the phosphorylation of glucose in an energetically favorable reaction

Answer 9

hexokinase

Question 10

Michealis-Mentere V=

Answer 10

V (rate of rx)= Vmax[S}/Km + [S]

Question 11

Inhibitor that binds at substrate site and prevents substrate binding

Answer 11

Competitive

Question 12

Inhibitor that increase Km, no change to Vmax

Answer 12

Competitive

Question 13

Inhibitor that bind an enzyme and inhibit its activity

Answer 13

Noncompetitive

Question 14

Inhibitor that decrease Vmax, no change to Km

Answer 14

Noncompetitive

Question 15

Inhibitor that binds a substrate and cause a conformational change

Answer 15

Allosteric

Question 16

DTTP

Answer 16

deoxythymide triphosphate

Question 17

Enzyme converts glucose to glucose 6-phosphate

Answer 17

hexokinase

Question 18

Enzyme converts phospoenolpyruvate (PEP) to pyruvate

Answer 18

pyruvate kinase

Question 19

Byproduct of PEP to pyruvate

Answer 19

ADP to ATP

Question 20

Enzymes affect on delta G?

Answer 20

No effect

Question 21

Michaelis constant, [S] at which v = 1/2Vmax

Answer 21

Km

Question 22

Maximum reaction rate

Answer 22

Vmax

Question 23

Low Km, higher Vmax

Answer 23

Activator

Question 24

high Km, lower Vmax

Answer 24

Inhibitor

Question 25

last enzyme of glycolysis, expressed in diff tissues

Answer 25

pyruvate kinase, PK

Question 26

Name the Diff PK

Answer 26

PK-M1, PK-M2, Pk-L, PK-R