transketolase , TK, rxns 6 and 8

Question 1

which rxns

Answer 1

6 or 8

Question 2

glycoaldehyde

Answer 2

comparison molecule, activated 2c we have when transferring hat is glycoladehyde deriv… carbonyl has become an OH….

TAZ attacks carbonyl as ylid, removal of a proton to allow for a cut, resonance stabilized carbanion, which allows for nuc attack of carbonyl carbon of R5P to E4P in rxn 8.
Gives F6P.