a,b,m,o,T and R forms Flashcards
in our context, a and b (phosphorylase):
a = more active form, (without AMP)
b = less active, needs AMP to be in more active of the less acitve possible conformers.
m and o
m = modified (did i add a phosphate)
o = original (dephospho)
T and R forms
T = tense conformer, less active form
R = relaxed conformer, more active form.
phosphorylase a more active form
m-a-R
(modified, a form, R form)
phosphorylase b as T form
o-b-T
least active, allosteric control, key in the muscle, if +Pi, is removing the allosteric effectors, unless there is a lot og G+G6P. if this happens, will shift to m-a-R, as the step before is just the placeholder.
level of liver GP activity depends on
fraction of “a” form present.