Moving hats: rxns 6-8 of PPP

Question 1

rxn 6

Answer 1

tops of the molecules, have 2 5C compounds, one of which is R5P and Xu5P which react to get 7C (S7P) and 3C (GAP) sugar.

Question 1

rxn 7

Answer 1

The C7 (S7P) and C3 (GAP) sugars from rxn 6 react, to get a C6 (F6P) and C4 (E4P) sugar.

Question 2

rxn 8

Answer 2

take a second copy of Xu5P and react with E4P to get F6P and GAP

Question 3

end products of PPP

Answer 3

F6P, F6P, GAP

Question 4

transketolase

Answer 4

catalyze rxn 6 and 8

Question 5

transaldolase

Answer 5

rxn 7

Question 6

trans

Answer 6

moving something across from one substrate to another. The “something” here is the hat of the molecule.

Question 7

Hats

Answer 7

2C hat from Xu5P goes on top of S7P and F6P. (3C left becomes GAP)

Then, in rxn 7, a 3C hat from S7P is transfered on top of GAP to give F6P.

another hat is 2C from Xu5P to E4P to give F6P again

Question 8

large vs small hat

Answer 8

small: have an OH and ketone

large hat: 2 kinds of OH with ketone in middle

Question 9

e- sink

Answer 9

two separate e- sinks, trans aldolase and transketolase in these…. sinks identical to aldolase (transaldolase) and TAZ (transketolase).

purpsoe of these is where you want to cut. Schiff: cut betwen a and b carbons of substrate.
TAZ: carbonyl and alpha positiojn