Transfusion Flashcards

1
Q

What determines blood type on RBC

A

Antigens

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2
Q

how many genes are in ABO antigens

A

3 (A, B, C)

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3
Q

what gene in the ABO is non functional

A

O gene

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4
Q

which genes are co-dominant

A

ABO

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5
Q

what do A and B gene code for

A

Transferase enzymes

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6
Q

Group A sugar is

A

acetylgalactosamine

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7
Q

Group B sugar

A

galactose

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8
Q

Group A and B antibodies are

A

anti-A and anti-B and predominantly IgM

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9
Q

group O antibodies are

A

anti- and anti B and mainly IgG

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10
Q

in group O anti-a and anti-b react against

A

A or B cells

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11
Q

group O can do what Group A and B can’t do , what is it?

A

cross the placenta

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12
Q

what ABO group is the most common

A

Group O

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13
Q

what is common to have in O moms

A

mild hemolytic disease fetus/ newborn

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14
Q

what it the universal donor

A

Group O

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15
Q

Group o have antibodies

A

Anti- A, Anti-B and anti- A,b

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16
Q

Group A:
antigens
antibody
subgroups

A

A
Anti-B ( mainly IgM)
A1( 80%) A2(20%)

17
Q

Group B
antigens
antibodies

A

B
anti-A

18
Q

Group AB
antigens
antibodies

A

A and B antigens
No antibodies

19
Q

what is the least common ABO group and the universal recipient/ donor plasma

A

Group AB

20
Q

for ABO testing the front type and reverse type should be?

A

opposites

21
Q

severe anemia is Hb

A

less than 7

22
Q

what do you need to watch if you keep transfusion blood

A

iron levels will rise due to there being iron in the additives

23
Q

plasma has no

A

viable cells

24
Q

plasma has

A

all the coagulation factors

25
Q

when do you typically use plasma

A

liver disease or pts with coagulopathy issues

26
Q

when do you give cryoprecipitate

A

low fibrinogen

27
Q

what are some modifications

A

Leukoreduction (Decrease WBC)

Irradiation( deactivation lymphocytes)

Washing ( removal of plasma protein etc)

freezing