Transfusion Flashcards
What determines blood type on RBC
Antigens
how many genes are in ABO antigens
3 (A, B, C)
what gene in the ABO is non functional
O gene
which genes are co-dominant
ABO
what do A and B gene code for
Transferase enzymes
Group A sugar is
acetylgalactosamine
Group B sugar
galactose
Group A and B antibodies are
anti-A and anti-B and predominantly IgM
group O antibodies are
anti- and anti B and mainly IgG
in group O anti-a and anti-b react against
A or B cells
group O can do what Group A and B can’t do , what is it?
cross the placenta
what ABO group is the most common
Group O
what is common to have in O moms
mild hemolytic disease fetus/ newborn
what it the universal donor
Group O
Group o have antibodies
Anti- A, Anti-B and anti- A,b