antiviral immunity Flashcards
what are the 3 responses
- intrinsic
- innate
- adaptive
Viral RNA are recognized by
Pattern recognized receptors on cytoplasmic and endosomal receptor
Transcription factor induce
interferon and cytokine expression
IFN-alpha/beta signals
receptor to induce antiviral gene expression
IFN- alpha, beta, producer cells are
all nucleated cells
IFN- alpha and beta induce
viral infection
IFN- gamma producer cells are
Tcells and NK cells
IFN-gamma induce
tcell receptor activation
IL-2, IL-12
what are the primary output of intrinsic cell defense
cytokines
what cytokines are key in antiviral immune responses
IFN-alpha/beta
IFN- gamma
TNF-alpha
IL-6
IL-12
Some viruses can
neutralize antibodies by blocking receptor or blocking the encoding
antigen presentation of antiviral component is mainly through
MHC class 1