antiviral immunity Flashcards

1
Q

what are the 3 responses

A
  • intrinsic
  • innate
  • adaptive
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2
Q

Viral RNA are recognized by

A

Pattern recognized receptors on cytoplasmic and endosomal receptor

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3
Q

Transcription factor induce

A

interferon and cytokine expression

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4
Q

IFN-alpha/beta signals

A

receptor to induce antiviral gene expression

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5
Q

IFN- alpha, beta, producer cells are

A

all nucleated cells

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6
Q

IFN- alpha and beta induce

A

viral infection

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7
Q

IFN- gamma producer cells are

A

Tcells and NK cells

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8
Q

IFN-gamma induce

A

tcell receptor activation

IL-2, IL-12

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9
Q

what are the primary output of intrinsic cell defense

A

cytokines

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10
Q

what cytokines are key in antiviral immune responses

A

IFN-alpha/beta
IFN- gamma
TNF-alpha
IL-6
IL-12

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11
Q

Some viruses can

A

neutralize antibodies by blocking receptor or blocking the encoding

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11
Q

antigen presentation of antiviral component is mainly through

A

MHC class 1

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