Granuloma Flashcards
what is granulomatous inflammation
chronic inflammation
what do granulomas consist of
- macrophages
- lymphocytes (Tcells)
immune granulomatous infections are caused
by agent and activated by Th1 cells
what forms on the outside of the granulomas
fibroblast
when are granulomas typically formed
when an indigestible substance is present
what is an example of foreign body
wood splinter, suture, something to large to be engulfed by macrophage
what are the two type of giant cells
foreign body type and langhans type
foreign body type the nuclei
evenly spread in the cell
langhans type the nuclei is
localized to the perimeter cell membrane
what is sarcoidosis
systemic non-infectoius granulomatous disease
what is the difference b/w caseating and non-caseating granulomas
caseating has necrosis