Transcription Factors

Question 1

Runx2

Answer 1

This is a transcription factor involved in the differentiation into bone cells

Question 2

Sp7

Answer 2

This is a leucine zipper transcription factor involved in the differentiation of mesenchymal precursors to bone cells

Question 3

HIF1A

Answer 3

This is the alpha subunit of the transcription factor HIF1

Question 4

AP-1

Answer 4

This protein is composed of Fos and Jun and is a transcription factor.

Question 5

Foxo

Answer 5

These are transcription factors which are regulators of longevity and are downstream of the insulin signaling pathway. These TFs are sensitive to nutrient deprivation and stress

Question 6

KLF4

Answer 6

This transcription factor is a zinc finger transcription factor that belongs to the SP1 family.

Question 7

SOX9

Answer 7

This transcription factor regulates the activity of genes responsible for skeletal development and sex determination.

Question 8

NF kappa B

Answer 8

This stands for Nuclear Factor light chain enhancer for activated B cells. This protein activates transcription of genes, is involved in cytokine production as well as cell survival.

Question 9

Srebp1

Answer 9

This is a sterol regulatory binding element transcription factor. It is a transcription factor that regulates lipid homeostasis.

Question 10

Fatty Acid Synthase

Answer 10

This is a multi enzyme protein that synthesizes fatty acids.