Cell Components

Question 1

MicroRNA

Answer 1

These are non-coding RNA molecules that regulate the expression of genes by several mechanisms

Question 2

Epiphyseal Growth Plate

Answer 2

This is the main site of longitudinal growth of the long bones.

Question 3

Regulon

Answer 3

This is a group of genes that are regulated as an unit, controlled by the same regulatory element, which is usually a repressor or an activator.

Question 4

Extracellular Matrix

Answer 4

These are a network of proteins and other molecules that surround and give support to cells and tissues in the body.

Question 5

CellChat

Answer 5

Examines cell cell interactions.

Question 6

Cellular Landscape (Healthy Articular Cartilage)

Answer 6

This constitutes of regulatory cells (RCs), effector cells (ECs), prefibrocartilage (preFCs), FCs, prehypertrophic cells (preHTC), HTC, homeostatic cells (HCs), reparative chondrocytes (RepCs).

Question 7

pySCENIC

Answer 7

This is a lightning fast python implementation of the SCENIC pipeline (Single Cell Regulatory Network Interference and Clustering) which enables scientists to infer transcription factors, gene regulatory networks and cell types from single cell RNA seq data)

Question 8

UMAP plot

Answer 8

This stands for Uniform Manifold Approximation and Projection plot and it determines how separable the classes are under consideration with respect to the selected group of features.

Question 9

Hematocrit

Answer 9

This is a ratio of the volume of red blood cells to the total volume of cells.

Question 10

Congenic

Answer 10

This is when organisms are identical except for variation in a limited genetic region.

Question 11

Dorsal Root Ganglion

Answer 11

This is a collection of sensory neuron cell bodies that are part of the peripheral nervous system.

Question 12

Annulus Fibrosus

Answer 12

The AF is part of the inner chondrogenic part and a fibrous outer part.

Question 13

Nucleus Pulposus

Answer 13

Constititutes of water, type II collagen, chondrocyte like cells and proteoglycans. This unique composite allows the NP to be elastic, flexible under stress like conditions and to absorb compression.

Question 14

hydrogel

Answer 14

This is a gel where the liquid component is water.

Question 15

Subchondral bone

Answer 15

This is bone tissue underlying the calcified cartilage and tidemark

Question 16

Lnc RNA

Answer 16

This is a long non-coding RNA (200nt) that regulates gene expression at the epigenetic, transcriptional, translational, post transcriptional and post translational methods in a variety of different ways

Question 17

GACAT3

Answer 17

LncRNA Gastric Cancer Associated Transcript 3