Tranquilizers

Question 0

meaning of tranquility

Answer 0

calming down of exited animal

Question 1

tranquilizers definition

Answer 1

are drugs which CALM DOWN an exited animal(tranquility)

Question 2

tanquilizers aka

Answer 2

ata-ractics

Question 3

classification of tranquilizers(TB2 PR)

Answer 3

thio-xanthine
benzo-diaz-epines
butyro-phenone
phenothiazine
rau-wolfia derivatives

Question 4

thioxanthine derivatives block which receptors ?

Answer 4

D1(+) & D2(+++) receptors in CNS

Question 5

name a thioxanthine derivative drug

Answer 5

chlo-pro-thixene

Question 6

except tranquilization,what are the other two effects of tranquilizers

Answer 6

anti-emetic effect

Question 7

MOA of benzo-diaz-epine derivatives

Answer 7

bind to the benzodiazipine receptor on GABA receptor(only facilitatory action)

Question 8

for dog what are the doses of DIAZEPAM in following purposes:

1. sedative
2. anticonvulsant
3. pre-anaesthetic

Answer 8

sedative= 1 mg/kg O/IV
anticonvulsant= 1-2mg/kg IV
preanaesthetic=0.2-0.5 mg/kg IM/IV

Question 9

MOA of action of butyrophenone derivatives

Answer 9

block dopamine receptors in CNS(D1 & D2)

block adrenergic receptors(peripherial)

Question 10

name 3 butyrophenone derivatives(HAD)

Answer 10

halo-peridol
aza-perone
dro-peridol

Question 11

most potent ANTIEMETIC

Answer 11

droperidol

Question 12

droperidol is used along with ________ as NEURO-LEPT-ANALGESIC

Answer 12

fentanyl

Question 13

among the 3 butryo-phenone derivatives which one is used for dogs and which one for pigs & horses

Answer 13

dog= haloperidol

pig & horse=azaperone

Question 14

name four phenothiazine derivatives(PACT)

Answer 14

promazine
ace-promazine
chlor-promazine
triflu-promazine

Question 15

MOA of phenothiazine derivatives

Answer 15

block D1 & D2 receptors in CNS

Question 16

other effects of phenothiazine derivatives except D receptor blocking

Answer 16

antiemetic effect
antagonize central stimulant action of sympatho-mimetics
hypothermia
block CAR
block adrenergic,H1,5HT receptors in CNS

Question 17

how phenothiazines produce antiemetic effect

Answer 17

by blocking dopamine receptors in CTZ

Question 18

how do phenothiazine derivatives cause hypothermia

Answer 18

by depleting catecholamines in hypothalamus

Question 19

tranquilizers block _______ avoidance response

Answer 19

conditioned

Question 20

unconditioned aviodance response is blocked by ________

Answer 20

sedatives

Question 21

do phenothiazine derivatives produce hypoglycemia or hyperglycemia?

Answer 21

hyperglycemia

Question 22

why phenothiazine tranquilisers should not be used for epileptic seizures?

Answer 22

as they lower seizure threshold

Question 23

rauwolfia derivatives mean compounds derieved from __________ plant

Answer 23

rauwolfia serpentina

Question 24

name a rauwolfia derivative

Answer 24

re-serpine

Question 25

re-serpine is used as _________ & __________

Answer 25

tranquilizer

anti-hypertensive