Muscle Relaxants

Question 0

skeletal muscle relaxant are used as adjunct to __________

Answer 0

anaesthetics

Question 1

define skeletal muscle relaxant

Answer 1

relax skeletal muscles

Question 2

classification of skeletal muscle relaxant

Answer 2

central acting

peripherally acting

Question 3

PERIPHERALLY ACTING skeletal muscle relaxants can be divided in to

Answer 3

neuromuscular blockers(NMB)
direct skeletal muscle relaxant

Question 4

neuromuscular blockers(NMB) can further be subdivided into

Answer 4

competitive

non-competitive

Question 5

competitive neuromuscular blockers(NMB) are aka _________

Answer 5

curariform drugs

Question 6

name 3 CENTRAL skeletal muscle relaxants (DiMaG)

Answer 6

diazepam
mef-enesin
guiaf-enesin

Question 7

name 3 COMPETITIVE neuromuscular blockers (TA2)

Answer 7

tubo-curaine
al-curonium
atra-curonium

Question 8

name 2 NON-COMPETITIVE neuromuscular blockers (DaS)

Answer 8

deca-methonium

succinyl-choline

Question 9

name 2 DIRECT skeletal muscle relaxant (DeeP)

Answer 9

dantrolene

phenytoin

Question 10

centrally action skeletal muscle relaxants aka ___________

Answer 10

skeletal muscle spasmolytics

Question 11

centrally action skeletal muscle relaxants act by interfering with _______ & _________

Answer 11

internuntial pathways in spinal cord

reticular activating system

Question 12

mefenesin & guaia-fenesin act as ______ agonist

Answer 12

glycine

Question 13

mefenesin & guaia-fenesin antagonise which convulsions?

Answer 13

stry-chnine

tetanus

Question 14

stry-chnine & tetanus convulsions can be antagonised by _________

Answer 14

• centrally acting skeletel muscle relaxants(mefenesin & guaia-fenesin )
• methocarbamol

Question 15

diazepam cause paralysis of muscles through ___________

Answer 15

gaba facilitation

Question 16

diazepam is used to antagonis convulsions of ____________

Answer 16

picrotoxin

Question 17

picrotoxin convulsions can be antagonised by

Answer 17

diazepam

Question 18

other 2 names of competitive NMB

Answer 18

curariform drugs

‘‘non-depolarizing” NMB

Question 19

tell the type and duration of paralysis caused my competitive NMBs

Answer 19

flaccid

30-60 min

Question 20

order of paralysis caused by competitive NMB

Answer 20

eyes>neck>limb>diaphragm

Question 21

noncompetitive NMB are aka ____________

Answer 21

depolarizing NMB

Question 22

the paralysis caused by non-competitive NMB are preceded by _________

Answer 22

muscular twichings

Question 23

type and duration of paralysis causes by non-competitive NMB

Answer 23

tonic

5-15 minutes

Question 24

why non-competitive NMB have shorter duration

Answer 24

as they are inactivated by pseudoCHE in liver

Question 25

effect of antiCHE agents on
competitive NMB
non-competitive NMB

Answer 25

antagonism

synergistic effect

Question 26

cat is most sensitive to competitive or non-competitive NMBs

Answer 26

non-competitive NMBs

Question 27

MOA of dantrolene(direct acting skeletal muscle relaxant)

Answer 27

interfere with release of Ca ions from sarcoplasmic reticulum of muscle fibres

Question 28

MOA of phenytoin(direct acting skeletal muscle relaxant)

Answer 28

interfere with function of ACh at motor end plate

Question 29

south american arrow poison is also known as

Answer 29

tubo-curaine(competitive NMB)

Question 30

MOA of cobra snak venom & clostridial toxin

Answer 30

prevent ACh rlease from motor nerve endings

Question 31

name the two cobra snake venoms

Answer 31

a-bungaro-toxin

b-bungarotoxin

Question 32

cobra snake venom are _______toxic

Answer 32

neuro