Tranexamic Acid Flashcards
1
Q
Tranexamic Acid Class
A
Antifibrinolytic
2
Q
Tranexamic Acid MOA
A
Inhibitor to the Lysine receptor found on plasminogen, preventing plasmin from binding to and ultimately stabilizing the fibrin matrix
3
Q
Tranexamic Acid Indications
A
Traumatic injuries within the last three hours with either:
signs and symptoms of hemorrhagic shock with SBP<90
AND/OR
significant hemorrhage with heart rate >/= 120
4
Q
Tranexamic Acid Contraindications (3)
A
Suspected traumatic brain injury
Pediatrics
Arterial or venous thromboembolism
5
Q
Tranexamic Acid Adult Dose
A
1g in 50-100mL over 10 minutes IVPB
6
Q
Tranexamic Acid Pregnancy Classification
A
B (not harmful to animals, untested in humans)
7
Q
Tranexamic Acid Peds Dose
A
NO
