Amiodarone

Question 1

Amiodarone Class

Answer 1

Antidysrhythmic

Question 2

Amiodarone MOA

Answer 2

Blocks potassium responsible for repolarization (causing increased action potential and prolonged refractory period). Excitability is decreased, preventing reentry mechanisms and ectopic foci from perpetuating tachyarrhythmias.
Interferes with beta-adrenergic receptors, calcium channels, and sodium channels (causing decreased SA node automaticity and AV node conductivity).

Question 3

Amiodarone Indications (2)

Answer 3

Cardiac arrest with ventricular fibrillation or ventricular tachycardia
Symptomatic (wide-complex) tachycardia with pulses

Question 4

Amiodarone Contraindication

Answer 4

High degree AV blocks

Question 5

Amiodarone Adult Cardiac Arrest Dosages

Answer 5

300mg IVP + 150mg IVP repeat

Question 6

Amiodarone Pregnancy Class

Answer 6

D (positive fetal risk)

Question 7

Amiodarone Adult Symptomatic Tachycardia Dose

Answer 7

BHO 150mg in 50-100mL IVPB

Question 8

Amiodarone Peds Cardiac Arrest Dose

Answer 8

BHO 5mg/kg max 300mg IVP

Question 9

Amiodarone Peds Symptomatic Tachycardia Dose

Answer 9

BHO 5mg/kg max in 50-100mg IVPB