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CFRN Studying > Toxicology > Flashcards

Toxicology Flashcards

1
Q

Hypothermia

A

Bradycardia
Decreased Q
Arrythmias, Osborn (J) Waves on EKG

“Core Temperature After Drop”

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2
Q

Hyperthermia

A

Mild - heat cramps
Moderate - heat exhaustion, loss of volume/electrolytes
Severe - heat stroke, rhabdomyolysis, renal failure, hot DRY skin, worsening CNS s/s.

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3
Q

Malignant Hyperthermia

A

Caused by continuous release of calcium into muscle fibers causing sustained contractions.

Antidote: Dantrolene. No CCB’s with dantrolene.

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4
Q

Drowning

A
  1. initial laryngospasm
  2. inability to breath
  3. drop in Pa02 releases spasm
  4. panic and hyperventilation
  5. worsening hypoxemia

Airway management. PEEP.

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5
Q

Snake Bites

A

Treatment:

Immobilize
Airway, ventilation, and circulatory support

Monitor for systemic reactions
Antivenin

How much time since bite?
Mark and track area around bite.

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6
Q

Hydroflouric Acid

A

H+ ions cause initial superficial burn injuries
Flouride continues to penetrate over time causing tissue necrosis
May render Ca+ and Mg+ neutralized.

Hyperkalemia, Hypocalcemia, Hypomagnesemia.

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7
Q

Caustic Ingestions

A

Airway control

NO antiemetics
NO gastric lavage
NGT suction
Supportive Care

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8
Q

Acetaminophen Toxicity

A

Phase 3 most important:

N/V
RUQ Abdominal Pain
Jaundice
DIC
Tender hepatic edge

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9
Q

ASA (salicylate) Toxicity

A

Phase 1: Hyperventilation, Alkuria
Phase 2: R Alk -> Metabolic Acidosis
Phase 3: Dehydration

Tinnitus**
Hyperventilation
Tachycardia
Depressed DTR (Deep Tendon Reflexes) Phase 4:B

Sodium Bicarb
Activated Charcoal

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10
Q

Beta Blocker Toxicity

A

Bradycardia
Hypotension
HYPOglycemia
Hypothermia

Fluid Resuc
Glucagon
Insulin

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11
Q

Calcium Channel Blocker Toxicity

A

Hypotension
Bradycardia/Arrythmias
HYPERglycemia

Calcium Loading
Glucagon
Insulin
Atropine
Pressors

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12
Q

Digitalis Toxicity

A

Yellow/Green Visual Aberration
PVC’s. Bradyarrhythmia’s, VT, Heart Blocks

Yellow Oleandar and Foxglove ingestion can mimick s/s.

EKG - T wave flattening, QT shortening.

Digoxin imune Fab (digibind)

NO CALCIUM
NO QUINIDINE, PROCAINAMIDE

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13
Q

Carbon Monoxide Antidote

A

Oxygen Washout

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14
Q

Cyanide Antidote

A

Amyl Nitrate, Na+ Thiosulfate,

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15
Q

Organophosphates Antidote

A

Atropine, 2-PAM

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16
Q

Methemoglobinemia Antidote

A

Methylene Blue

17
Q

Anticholinergic Antidote

A

“ine”

Physostigmine

18
Q

Coumadin Antidote

A

Vitamina K, FFP

19
Q

Heparin Antidote

A

Protamine Sulfate

20
Q

Beta Blocker/CCB Antidote

A

Glucagon, Insulin, Calcium

CFRN Studying (23 decks)

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