Oxygen Delivery Flashcards
1
Q
Delivery of Oxygen Equation
A
DO2=QxCaO2
Q=SVxHR
SV=Preload+Afterload+Contractility
CaO2=[1.34xHbgx(SaO2)] + Pa02 x 0.003
2
Q
Measuring O2 Delivery
A
Hemoglobin = 1.34 ml of oxygen
Ex. 1.34 x 15 (hgb) x 1.0 = 20 ml/dL
Simplify = 20mL/100mL = 0.2 mL
Standard adult = 5 L/min or 5000mL
0.2mL ox oxygen x 5000mL = 1000mL oxygen per minute.
Divide by 1.7m2 to account for BSA.
= O2/min/m2
3
Q
Fick Formula
A
Cellular Uptake of O2
Same as D02 but using Sv02 as a standard.
(1.34 x hbg (g/dL) x SvO2)
4
Q
What is the biggest aspect of oxygen delivery? (Possible Test Question)
A
ALWAYS Hemoglobin!
5
Q
Anaerobic Metabolism
A
- Glycolysis - Pyruvate
- Pyruvate - Lactic Acid
- if O2 is low or not present, then lactic acid accumulates.
6
Q
Types of hypoxia
A
- Hypoxic Hypoxia - Deficiency in alveolar exchange
- hypemic hypoxia - reduction in O2 carrying capacity
- Stagnant hypoxia - Obstructive shock, reduced cardiac output, PE, shock states.
- histotoxic hypoxia - a result of poisoning or metabolic disorders such as cyanide, ETOH, or CO poisoning.