Topical Therapeutics in Dermatology

Question 1

Powder in water (some oil in water)?

Answer 1

Lotions/Solutions

Question 1

This is a class 1 topical steroid not to be used on the face, skin folds, or groin.

Answer 1

clobetasol

Question 2

1 gram of cream covers approximately ____ area of skin.

Answer 2

10 cm x 10cm

Question 2

1 gram of ointment spreads 10% further than the same amount of _____.

Answer 2

cream

Question 3

Approximately 20 g are necessary to treat ____.

Answer 3

the entire body of an adult man

Question 3

Name the 3 topical glucocorticoids we need to know.

Answer 3

1. hydrocortisone 2. triamcinolone 3. clobetasol

Question 4

Pressurized collections of gaseous bubbles in a matrix of liquid film?

Answer 4

Foams

Question 4

Approximately ____ are necessary to treat the entire body of an adult man.

Answer 4

20 g

Question 6

Semisolid emulsion in alcohol base?

Answer 6

gel

Question 7

What are the drug factors affecting percutaneous absorption?

Answer 7

• Active drug concentration • Composition of the vehicle • Molecular size of the drug or prodrug • Lipophilicity of the drug

Question 8

What is an FTU?

Answer 8

amount of ointment dispensed across distal 3rd of index finger equaling 0.5g

Question 9

_____ of _____ spreads 10% further than the same amount of cream.

Answer 9

1 gram; ointment

Question 11

What is triamcinolone?

Answer 11

a class 4 topical steroid cream or ointment used for moderate dermatoses

Question 12

Gel?

Answer 12

Semisolid emulsion in alcohol base

Question 13

Water in oil?

Answer 13

ointment

Question 14

What is clobetasol?

Answer 14

a class 1 topical steroid cream or ointment not to be used on the face, skin folds, or groin

Question 15

This is a class 4 topical steroid cream or ointment used for moderate dermatoses.

Answer 15

triamcinolone

Question 17

Creams?

Answer 17

oil in water

Question 19

What are the pt factors affecting percutaneous absorption?

Answer 19

•Presence of barrier disruption • Anatomic location (including thickness of the stratum corneum) • Skin hydration • Occlusion

Question 20

____ of cream covers approximately 10 cm x 10cm area of skin.

Answer 20

1 gram

Question 21

Oil in water?

Answer 21

cream

Question 22

What is an Ointment?

Answer 22

water in oil

Question 23

Foams?

Answer 23

pressurized collections of gaseous bubbles in a matrix of liquid film

Question 24

Lotions/Solutions?

Answer 24

Powder in water (some oil in water)