Topic 1 Wood Flashcards
How do you find the risk rating?
Multiply the likelihood by the severity
Actual Risk
Actual risk is based on many studies and large sample sizes
Perceived risk
Perceived risk is very different to actual risk and can be based on cultural norms rather than any data
Key Factors to overestimate risk
Unfamiliar Unknown Dreaded Unfair Not in control Immediate severe outcome
Key Factors to underestimate risk
Voluntary Familiar Enjoyable Common Effect is in the long term
Epidemiology
A study of incidents of a disease in populations to find out how, when and where they occur and to find a method of preventing or controlling it
Morbidity
the number of people currently living in the diseased state
Mortality
the number of people who die from a specific disease (within a time frame)
Toxicology
the study of the nature, effects, detection and treatments of poisons
Genetics
the study of heredity and the variation of inherited characteristics
Ecology
the study of the relationships between organisms and their environment
Features of a good study
Clear aim - test a clearly stated hypothesis
Representative sample - avoid bias in the group being studied e.g. age, gender
Valid and Reliable results - consistency of approach, similar results are used for comparison
Null Hypothesis
reverse of hypothesis; assume there is no effect (something you want to disprove because then the hypothesis must be correct)
Cohort study
- Follow a group of people over time
- See who develops the disease
- Correlate between risk factors and actual disease development
Expensive, time consuming, large scale
Case control study
- Follow groups of people over time
- Compare those with and without the disease
- Look at previous exposure to risk factors and link to disease
Smaller scale, relatively inexpensive
Correlation
When one variable changes there is a change in an accompanying variable
Causation
A change in one variable is directly responsible for a change in another variable
Treating CVD Lifestyle Changes
Give up smoking
Exercise more
Change Diet
Reduce alcohol intake
Treating CVD Medical
Diuretics Beta Blockers ACE inhibitors Statins Anticoagulants Platelet inhibitors Calcium channel blockers
Surgery - stent or bypass
Diuretics (Antihypertensives)
Increase volume of urine –> lowers blood pressure
Occasional dizziness, cramps, nausea
Beta blockers (Antihypertensives)
Block the heart’s hormone response –> less frequent/ powerful beat lowering blood pressure
ACE Inhibitors (Antihypertensives)
Blocks angiotensin production and keeps blood pressure low
Arrythmia, kidney problems, cough, dizziness
Statins
Block enzyme that produces LDL cholesterol –> lowers cholesterol levels
Nausea, diarrhoea, inflammatory response
Anticoagulants
Reduce the risk of blood clot formation
Uncontrolled bleeding
Platelet inhibitors (e.g. aspirin)
Make platelets less sticky so reduces chance of a blood clot forming
Hypothesis testing statistics
Compare one set of data with another:
t-test, chi-squared, Mann-Whitney U, Spearman’s rank
Descriptive Statistics
Tell you something about one set of data:
mean, median, mode, standard deviation
BMR - Basal Metabolic Rate
The energy required by your body for maintaining your essential body processes including; pumping of the heart, breathing and maintaining body temperature