Topic 1 - INTRO TO PHYSIOLOGY Flashcards
What is physiology?
study of how the body functions
What is Homeostasis
the ability to maintain relatively stable conditions in the internal environment (despite changes in the external environment)
- cells can only survive within a narrow range of conditions
- body conditions must be maintained within physiological limits
- conditions controlled include:
- pH, temperature
- CO2
- O2
- blood pressure
- ICF + ECF volumes
Homeostasis
organ systems function together to ______________
maintain homeostasis
Homeostasis
disease = ?
failure to maintain homeostasis
homeostasis
nervous and/or endocrine system(s) control what?
and act to what?
all other systems (control systems).
act to:
- maintain homeostasis
- permit departures from homeostasis in a controlled manner
e.g. pregnancy, growth, sudden fright
Homeostasis regulation:
- Change in internal environment must be detected or anticipated
- then nervous and/or endocrine systems respond, altering system(s) responsible for that condition
Homeostasis regulation
what are 2 the types of Nervous System/Endocrine responses?
- anticipatory responses
- feedback machanisms
Homeostasis Regulation
NS/Endocrine responses:
Anticipatory responses
- e.g. increased respiratory rate at start of excercise → proprioreceptors (NS senesory receptors) signal movement before a change in internal conditions occurs (gases in blood)
- may also be learned or behavioral
- e.g. put on coat
Homeostasis Regulation
NS/Endocrine responses:
Feedback mechanisms
- mechanisms that respond to a change in the system
- consist of set points receptors, control areas and effectors
- set point = range of values of variable (e.g. body temperature) that do not bring about a response (i.e “normal range”)
- variable is monitored by receptors ⇒ info (input) fed back control area (NS, endocrine gland) controls the effector (output)
Homeostasis Regulation
NS/Endocrine responses:
What are the two types of feedback mechanisms?
- negative feedback
- positive feedback
Homeostasis Regulation
NS/Endocrine responses:
Feedback mechanisms ► Negative feedback
- most common homeostatic control mechanism
- result of “output” - variable moves back toward the set point i.e. in opposite (negative) direction to the change that triggered the response
- e.g. body temp (=variable): set point = 36 - 37.8ºC. If increased temp. (40º):
- result = increased core blood to decrease skin surface and sweat evaporates = heat loss & temp. (opposite direction of change)
- e.g. 2: decreased temperature ⇒ shiver ⇒ increased temperature.
- set point can change e.g. in fever
Homeostasis Regulation
NS/Endocrine responses:
Feedback mechanisms ► Positive feedback
- less common - NOT homeostatic
- output intensifies the input
- e.g. childbirth - labour
- continues until endpoint (=baby born)
set point can change
true or false?
true