Tissue Lecture 2 Flashcards
Exocrine Glands
Definition, Examples
Definition: Glands that release secretions into ducts or onto the surface of epithelium.
Examples: Sweat glands, sebaceous glands, lacrimal glands, pancreatic acinar cells.
Endocrine Glands
Definition, Examples
Definition: Glands that release secretions directly into the bloodstream.
Examples: Testes, ovaries, pancreas, pituitary gland.
Merocrine Glands
Definition, Examples
Definition: Exocrine glands where secretions are released via vesicles through exocytosis.
Examples: Pancreatic cells, salivary glands.
Apocrine Glands
Definition, Examples
Definition: Exocrine glands where secretions accumulate on apical surfaces and are released by pinching off a portion of the cell.
Examples: Apocrine sweat glands, mammary glands, ceruminous glands.
Holocrine Glands
Definition, Example
Definition: Exocrine glands where secretions accumulate in the cytosol and the entire cell dies, acting as a secretory vesicle.
Example: Sebaceous glands.
General CT Terms
Blasts, Chondroblasts, Osteoblasts, Fibroblast, Cytes
Blasts: immature cells that can replicate
Chondroblasts: cells that result in cartilage
Osteoblasts: cells that result in bone
Fibroblast: cells that produce ECM
Cytes: mature cells (chondrocytes, osteocytes, fibrocytes, etc.)
Structure of Connective Tissue
- Specialized cells
- Extracellular Matrix (ECM)
Two components of ECM:
Extracellular protein fibers
Fluid called ground substance
Extracellular Matrix (ECM)
- Matrix = Substance surrounding cells including solutes that ‘fill’ space
Made up of:
Ground substance
Fibers (collagen, elastin, reticular)
ECM - Ground Substance
- Fills space between cells and fibers
- Serves as support and binding for cells
Consists mainly of: - Water (H2O)
- Polysaccharides (GAGs)
- Proteins
ECM - GAGs
Glycosaminoglycans
- Long, linear polysaccharides with repeating units
- Contains amino groups
ECM - Fibers (3 types)
- Provide strength, structure, and movement to tissue
Three types found in ECM:
Collagen
Elastic
Reticular
ECM - Collagen Fibers
- Made up of collagen protein
- Provides majority of strength and stability to cartilage, tendons, and ligaments (appears white)
ECM - Elastic Fibers
- Made up of elastin and fibrillin protein
- Allows elasticity of fibers (up to 150% of original length)
ECM - Reticular Fibers
- Made up of collagen but thinner and more widespread forming a network
- Aids in support and strength
ECM - Reticular Fibers (Stroma)
- Forms stroma (“bed or covering”) of some organs
- Supportive framework of organs, especially solid organs
- Examples: spleen, kidney, liver