Tissue Engineering Flashcards

1
Q

Tissue engineering

A

Our ability to CELL CULTURE
our ability to build materials that are BIOCOMPATIBLE

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2
Q

Purpose of cell culture

A

understand what cells are going to when we maintain outside of the body

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3
Q

autologous

A

donor to donor
-immune acceptable

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4
Q

allogeneic

A

donor to recipient
-same species

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5
Q

syngeneic

A

genetically identical donor
-homozynous twin

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6
Q

xenogeneic

A

cross-species
-animal cells present in human patient

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7
Q

Stem cells

A

undifferentiated cells with the ability to divide in culture and give rise to different forms of specialized cells

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8
Q

How are tissue cultures done?

A

On a petri dish or bioreactor

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9
Q

Bioreactor

A

to simulate the bodies conditions
-any device that supports a biologically active environment

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10
Q

Xenogenetic Transplant

A

The donor and the recipient are memebers of different species (xenograft)

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11
Q

Allogenic transplant

A

donor and recipient are the same species but are not genetically identical
(allograft)

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12
Q

Autologous Transplant

A

Cells from patient being isolated and given back to the same recipient (autograft)

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13
Q

Bone marrow

A

Bodys main blood cell factory

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14
Q

Bone marrow transplant

A

The purpose is to put healthy stem cells in place of unhealthy ones
-If bone marrow does not work correctly the person can become very ill (leukemia)

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15
Q

Level 1 complexity of tissue engineering

A

Flat structures that are made up of just 1 type of cell

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16
Q

Level 2 complexity of tissue engineering

A

tubes like blood vessels and urethras which have 2 types of cells

17
Q

Level 3 complexity of tissue engineering

A

hollow non-tublar organs like the bladder and stomach have complex structures and functions

18
Q

Level 4 complexity of tissue engineering

A

solid organs like th kidney,heart, and liver
-Have many differnt types of cellls and also require blood supply

19
Q

Limitation of tissue engineering

A

Vascularization
-need adequate blood supply

20
Q

Vascularization

A

growing blood vessels into tissue to improve oxygen and nutrients