Biomaterials Flashcards

1
Q

Biomaterials

A

-restoring function and facilatating healing for people after injury or disease
-may be natural or synthetic, must be BIOCOMPATIBLE

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2
Q

Biocompatability

A

-the ability of a material to perform with an appropriate host response in a specific application

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3
Q

Advantages of metals

A

Most commonly usef
- strong, resist fracture high mechanical strength
-easily formed into complex structures (deformable)

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4
Q

Disadvantages of metals

A

-susceptibility to corrosion
-stress sheilding
-wear debris

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5
Q

Different kinds of metals

A

-iron-base alloys(stainless-steel)
-cobalt-base alloys
-titanium base alloys

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6
Q

Material selection criteria of metals

A

-mechanical loading requirements
-chemical + structural properties of the material

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7
Q

Advantages of glass and ceramics

A

-Very biocompatible with bone
-Low wear rates, resist to microbial attacks
-very stiff and high melting poin t

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8
Q

Disadvantages of glass and ceramics

A

-brittle
-potential to fail catastrophically
-difficult to construct
-ceramics cannot be reshaped

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9
Q

Bioactive ceramics

A

-certain compositions of glass and ceramics that stimulate bonding
-important in securing orthopedic medical devices (such as replacement hips, knees and spinal fusion)

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10
Q

Bone grafts

A

Made of synthetic material
-work by stimulating the body to form natural bone

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11
Q

Spinal fusion

A

Join together 2 bones(vertebrae) in the spine to stop movement between them

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12
Q

Polymers

A

-a large molecule composed of repeating structural units (monomers)
-they resemble natural materials
-their chemical bonding + structire can be modified to have flexible, rigid, low strength or high strength materials
-can be permanent or biodegradable

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13
Q

Natural polymeric materials

A

wool,silk, and natural rubber

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14
Q

Synthetic polymers

A

nylon, PVC, polystrene, polyethylene, polypropylene, silicone

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15
Q

Advantages of natural materials

A

-more biocompatible then synthetic
-can recognize and process whats around them

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16
Q

Disadvantages of natural materials

A

lot to lot variability
-structural complexity
-inadequate biomechanical properties

17
Q

Composites

A

Made by mixing 2 components, molding, compacting, or chemically reacting them together
Fiberglass or Carbonfiber

18
Q

Vascular grafting

A

-the use of tansplanted or prosthetic blood vessels in surgical procedures
-surgical bypass treats narrowed arteries by creating a detour around the blocked section
-always blood to flow through a new pathwsy

19
Q

Coronary artery bypass graft

A

issued for people with occluded coronary arteries (can be more than 1 graft required)

20
Q

Atherosclerosis

A

-Thickening of arterial wall, formation of plaque
-Leads to loss of suffiecient blood to the myocardium which can be a heart attack

21
Q

Vascular Stents

A

-Used to provide support for a blood vessel
- Placed by inflating a ballor within the narrowed blood vessel then deflating it to place the stent

22
Q

Complications of Vascular stents

A

vascular injury or regrowth of scar tissue around the stent which renarrows the blood vessel
-Drug can be used to prevent blockage