Tigecycline (Tygacil) Flashcards
1
Q
Is Tigecycline (Tygacil) Bacteriocidal or Bacteriostatic?
A
BACTERIOSTATIC
2
Q
Why don’t you want to use Tigecycline (Tygacil) to treat bacteremia?
A
Does NOT attain high serum concentrations
3
Q
Why is Tigecycline (Tygacil) considered a “3rd tier” ABX reserved for “last ditch effort” type situations?
A
higher all cause mortality (3 vs 4%)
probalby due to BACTERIOSTATIC
4
Q
Which ABX can be used for complicated skin infections, intra-abdominal infection, and community acquired pneumona?
A
Tigecycline (Tygacil) but:
really only use when several allergies to other antibiotics
5
Q
What bugs are covered by Tygecycline (Tygecil)?
A
- MRSA/VRE
- Gram negative bacteria (Carbapenem resistant Enterobacteria=CRE)
- Acinetobacter (not Pseudomonas)
- Anaerobes (GI infections)
6
Q
What ABX covers:
- MRSA/VRE
- Gram negative bacteria (Carbapenem resistant Enterobacteria=CRE)
- Acinetobacter (not Pseudomonas)
- Anaerobes (GI infections)
A
Tygecycline (Tygecil)
