Colistin Flashcards
1
Q
What is Polymixin E known as?
A
Colistin
2
Q
What should be used for really resistant PEK bugs and SPACE bugs, the “kitchen sink”?
A
Colistin
3
Q
Is Colistin Bacteriocidal or Bacteriostatic?
A
Bacteriocidal
4
Q
What are the 2 common adverse reactions to Colistin?
A
Nephrotoxicity
Neurotoxicity
5
Q
What unique routes of administration are there for Colistin?
A
Nebulization (Inhaled)
Intrathecal (rare)
6
Q
In what form is Colistin administered?
A
Pro-drug format as
• Colistimethate sodium (IV)
7
Q
What bugs are covered by Colistin?
A
-PAN-RESISTANT G– ORGANISMS
- Pseudomonas and Acinetobacter (SPACE)
- Resistant PEK bugs (carbapenem resistance Enterobactericae CRE)
