Thyroif Flashcards

1
Q

Thyroid gland

Weighs -??
Consists of ???
Produces ???
Parafollicular cells secrete??

A

9-30g
Two lateral lobes connected by an isthmus
T3 and T4
Calcitonin

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2
Q

Thyroid hormone synthesis

Which is more produced ?
Which is more metabolically active?

A

T4
T3

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3
Q

T4 is converted in the ______,_____, and ______ to T3

A

Liver
Kidney
Muscle

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4
Q

T3 and T4 are bound to _______, including ______,______, and ________

A

Plasma proteins

TBG ; TBPA; albumin

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5
Q

Drug dosage for simple goitre

A

0.15-0.30ug daily of L-thyroxine

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6
Q

Treatment for permanent paralysis

A

Arytenoidectomy

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7
Q

Post operative care of malignant goitre

A

Reactional hemorrhage
Respiratory distress
Thyrotoxicosis
Parathyroid insufficiency
Wound infection

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8
Q

Symptoms of hypothyroidism
Hint:physical and mental

A

Physical:weight loss,menorrhagia,muscle fatigue,cold intorlerance,hoarseness of voice

Mental:failing memory,slow thought,speech and action

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9
Q

Toxic symptoms
Hint:HYPER

A

SEEN(CEEN)
C-CVS;palpitation, respiratory distress,chest pain,ankle swelling
E-visual disturbance,double vision,difficulty closing eye lid,protuding eyeball
E-visual disturbance,double vision,protuding eyeball
N-neuromuscular :tremors,anxiety

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10
Q

Signs hyperthyroidism

A

Parts of body:Palmar erthyema,pretibial myxoedema, exophthalmos,ophthalmoplegia diplopia,lid retraction,lid lag

Bruit,tremor

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11
Q

Simple Vs toxic goitrehint:diffused and modular

A

Diffused-diffused hyperplastic,toxic diffused toxic
Nodular-simple multinodular,toxic modular

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12
Q

Treatment simple Vs toxic
Hint:one wants more

A

Simple -l-thryoxine,iodine therapy, thyroidectomy,lobectomy

Toxic-antithyroid,radioactive iodine,subtotal thyroidectomy

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13
Q

Indications for surgery
simple Vs toxic

A

Simple-sec thyrotoxicosis Vs primary
Pressure symptoms

The others ..check it

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14
Q

Two drugs that prevent iodine trapping

A

Propyl thiouracil and sodium perchlorate

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15
Q

Cabamazole
Hint:Coba

A

Prevent binding of iodine to tyrosine
Prevents coupling of mit and sit

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16
Q

Treatment for early stage simple goitre

A

Lugols iodine/potassium iodide for diffused hyperplastic

17
Q

CVS symptoms

A

Palpitations-earliest
Increase thyroid receptors on myocyte

18
Q

GIT
Hint:cd,e

A

Increase calorigenesis
HyperDefecation
Excessive eating

19
Q

Post operative complications
Late occurrence of insufficient thyroid is -
Exacerbation of hyperthyroidism is -

A

Hypothyroidism
Thyrotoxicosis

20
Q

Signs of hyperthyroidism

A

Eyes-exopthalmos,ophthalmoplegia,diplopia
Hands -tremor,palamr erythema
Heart -atrial fibrillation,cardiac failure
Thryoid-bruits
Feet-pretibial myxoedema

21
Q

Signs of hypo

A

Eyes:periorbital puffiness(p-p like o-o)
Heart:bradycardia
Legs and hands:delayed relaxation of ankle jerks,bradykinesia,cold extremities
Thryoid:hoarse voice

22
Q

Function of thyroid hormones
Hint:think hyperthyroidism

A

Energy-glycogenolysis and hepatic gluconeogenesis,cholesterol synthesis and degradation
Brain-developmebt
Skeletal framework-matiration ,bone and protein turnover
Heart-inotropic and chronotropic
Git-increased motility