Sepsis Asepsis and Sterilization Flashcards

1
Q

• Sepsis- state of _________________

• The word Asepsis: Greek “a” to ________, “sepsis”= _____________

A

infection by microbial organisms

deprive

putrefaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Asepsis presumes the risk of __________ contamination is minimal.

A

airborne

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Aseptic method can be _________ or ________

A

medical

surgical

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Medical asepsis: objects are classified as ________ or ________

A

clean or dirty

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Sources of infection

• Endogenous: _____,_______,______

Exogenous: _________,________,_________

A

Skin
Mucous membranes
Viscera

Theatre environment
The Surgeon
other theatre staffs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Some Principles of asepsis

• Surgeon’s preparation for surgery
• Surgeons with an ________ should not operate
• Surgeon with ______,_______,_____ on the hand and forearm should not operate
•________/__________ swabs

A

URTI

cuts, abrasions, rashes

Nasal/pharyngeal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Asepsis-theatre work ethics

• Always _________ the sterile field; avoid _________ to the sterile.
• Keep sterile instruments _________ level
• Avoid reaching ________________.
• Do not _________,_______,_______ over a sterile field
• Keep sterile field dry.
• Sterilized instruments should have labels showing contents, time and date and

A

face ; tuning side or back

above waist or table

across the sterile field.

speak, sneeze or cough

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Asepsis-theatre work ethics contd
• __________ before a surgical procedure removes as many microorganisms from the hand
• Sterile gowns
• Gloving
• Carry linens away from the body
• Do not raise dust-avoid __________

A

Scrubbing

shaking linens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Asepsis:Patient-related factors
•______ hospital stay before surgery and after is desirable
• Control patient related _____________ that increases susceptibility to sepsis
• Preoperative showering –no evidence
• Change patients to _____________ before transporting them to theatre. Remove nail polishes, jewelleries
• Remove ___________ before entering the theatre

A

Short

co-morbid factors

clean theatre gown

ward blankets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Asepsis-theatre related factors

• Air-borne mode of transmission unusual but should be considered in surgeries involving _________.
• Circulating airborne pathogens is related to the ________ in the theatre and their _____________ and __________
• Door leading to the theatre should not be _________ as it affects ventilation system

A

implants

number of people

movements and theatre clothing worn.

left open

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Theatre ventilation systems should be _________ or ___________ mode(Theatre pressure(<or>?) outside rooms)</or>

A

plenum

positive air pressure

>

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Decontamination

Concept applied to __________________ to ensure safety in their further use on patients and handling by the theatre staff

A

re-usable medical instruments

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Decontamination involves:

_________
_________
___________

A

Cleaning
Disinfection
Sterilization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

decontamination

Cleaning removes ________ contamination not necessarily _____________

• Disinfection is a process that reduces the ________________. _____,_______ may be unaffected

• Disinfectants are ________ preparations used on ____________.

A

visible; destroy microorganisms.

number of viable organism to an acceptable level

Viruses bacterial spores

Chemical; inanimate objects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Cleaning is a prerequisite to __________ and __________

A

disinfection and sterilization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Disinfectant May be toxic to tissues

T/F

17
Q

Disinfection of surgical instruments •

Disinfection may be via:
•__________ for heat-tolerant instruments. ________,________
• Kills most _______

• Chemical disinfection: good where —————— cannot be used
• eg 2percent _________ and ________

A

Moist heat

rigid proctoscope, speculum; viruses

moist heat

glutaraldehyde and peracetic acid

18
Q

Moist heat disinfection may be used for heavily contaminated instruments prior to cleaning

T/F

19
Q

Levels of chemical disinfection

Differentiate

High level disinfection

Intermediate disinfection

Low level disinfection

A

High:can handle everything, including spores but that’s when it’s not in a high concentration

Intermediate:inactivates mycobacterium, and all the others, except bacterial spores

Low: kills most bacteria , some viruses, some fungi , but can’t be relied on to kill the resistant microorganisms such as bacterial spores or tubercle bacilli

20
Q

Medical devices Versus risk of infection

Critical

Semi-critical

Non-critical

A

Critical : enters normal body sterile tissue . Must be sterilized

Semi-critical:contact mucous membranes. High level disinfection, sterilization

Non-critical: contact intact skin. Intermediate or low level disinfection

21
Q

Selection of chemical disinfectants in clinical practice

• Low Level disinfectants:
__________
____________

Intermediate level disinfectants
________
_______
___________

High level disinfectants
____________
_______________

A

Phenolics
Quatenary ammonium compounds

Alcohols
Hypochlorites
Iodine/iodophors

Hydrogen peroxide
Glutaraldehyde

22
Q

Antiseptics
• An antiseptic is a type of _________, which _________ or ______________ micro-organisms on living tissues without ____________ effects when applied to surfaces of the body or to exposed tissues.

A

disinfectant

destroys or inhibits growth of

causing injurious

23
Q

Clinical applications of anti-sepsis

• prevent infection of _________ or ______
•applied to _______ and _______ to prevent sepsis by removing or excluding microbes from these

A

unbroken skin or mucous membranes

Burns and open wounds

24
Q

Ideal antiseptics
• _______ action
• _______ action
• _______ effect
• _______
• _______ reaction

A

Rapid
Broad
Persistent
Safe
Minimal

25
Chlorhexidine plus cetrimide ( ________ ) Povidone-iodine( ___________ )
Savlon Betadine
26
___________________ (Savlon)
Chlorhexidine plus cetrimide
27
_____________________ (Betadine)
Povidone-iodine
28
Sterilization • (Partial or Complete?) destruction of all viable microorganisms including _____,______,______
Complete spores, viruses and mycobacteria.
29
Modes of sterilization • __________ • __________ • __________
Physical • Chemical • Ionizing radiation
30
_________ is the Principle behind the autoclave
Steam under pressure
31
SSIs are infections along ____________ related to the operation within _________ for a non prosthetic /_______ for a prosthetic surgery.
the operative tract 30 days 1 year
32
IDENTIFYING SSIs Based on: •Site & extent ● Incisional infections -Superficial: ______ only ± _________ -Deep: __________(_____ and _____) ● Organ/ Space infections: ____________
Skin; ; subcutaneous tissue Deep soft tissue (fascia and muscle) Organ/space
33
Minor SSI -may ___________ or ____________ -not associated with ____________ or _______ signs. •Major SSI -discharges ___________ -needs a ___________ to drain it. -systemic signs of SIRS-tachycardia, pyrexia, raised white count.
discharge pus; infected serous fluid excessive discomfort; systemic significant quantities of pus secondary procedure
34
Quantitatively, the risk of SSI is markedly increased if a surgical site is contaminated with >_____ microorganisms per gram of tissue. •The dose of contaminating microorganisms to produce infection lower in presence of ________. E.g 100 staphylococci per gram of tissue introduced on ________
105 foreign material silk sutures
35
Risk Factors for SSI: Patient factors •_____ •Diabetes –________ –Glucose >______ mg/dL post period (<48 hours) •Nicotine use: delays primary wound healing •Malnutrition •Obesity: ____% over ideal body weight •Prolonged preoperative stay: surrogate of the severity of illness and comorbid conditions •Coexistent infections at a remote body site •Altered ____________
Age HbA1C ; 200 20 immune response
36
LOCAL INFECTIONS •Abscess –Signs of acute inflammation – _______ organisms implicated –release of cytokines,O2 free radicals –Tissue ______ and _______ –Drainage with _______ –Guided _______ –Antibiotics if not ________ –Healing by ______________
Pyogenic necrosis & suppuration curettage aspiration; localised secondary intention