Thyroid and Pancreas Flashcards
1
Q
in formation of T3/T4, what is thyroglobulin
A
globulin + tyrosine, binds to iodine to make monoiodothyronine
2
Q
what causes hypothyroidism
A
- lack of iodine
- hashimotos thyroiditis
- trauma
3
Q
what are the symptoms of hypothyroidism
A
- sleepiness, sluggish
- slow heart rate, low BP
- increased weight
- constipation
- mental slowness
- decreased hairgrowth
- husky voice
- dry skin
- widespread odema
4
Q
what causes hyperthyroidism
A
- graves disease
- inflammation of thyroid gland
5
Q
symptoms of hyperthyroidism
A
- intollerant to heat
- increased sweating
- weight loss
- diarrhoea
- tachycardia and raise BP
- nervousness, tremors
- exopthalalmos - prtuding eyeballs
6
Q
what is produced in the Islets of Langerhans:
alpha cells and
beta cells
A
alpha: glucagon
beta: insulin
7
Q
what do the acinal cells produce
A
enzymes that break down protein, lipids and carbohydrates
8
Q
how does glucose enter the cell
A
through passive diffusion with the help of GLUT4 transporters
9
Q
what effect does somatostatin have on insulin and glucose
A
inhbits their secretion
10
Q
what is the function of pancreatic polypeptide
A
self-regulate pancreatic secretion activities