Thyroid Flashcards
Hashimotos
Hypothyroidism
Drugs that cause hyperthyroidism:
Iodide
Amiodarone
Interferons
What is the treatment of choice in Graves’ disease ?
RAI -131
PTU has a BBW for ____________
Liver damage and acute liver failure
What is the preferred agent in thyroid storm?
PTU
What is the pregnancy category of PTU ?
D
If a pregnant women has hyperthyroidism, what do you give them?
PTU for women trying to conceive or in the first trimester. Then change to methimazole for 2nd and 3rd trimesters due to increased risk of liver toxicity from PTU
Normal range of thyroxine
0.8-1.7
High TSH
0.3-3.0
If a patient is having palpitations, tremor, and tachycardia, what else can be given besides thyroid meds to reduce these?
BB
________inhibit synthesis of thyroid hormones by blocking the oxidation of iodine in the thyroid gland; PTU also inhibits peripheral conversion of t4-t3
Thionamides
________inhibit secretion of thyroid hormone; T4-t3 levels will be reduced for several weeks but effect will not be maintained
Iodides
What are the 2 Thionamides
PTU
methimazole (tapazole)
What are the iodides ?
Potassium iodide and iodine solution (Lugols solution)
SSKI- saturated solution of potassium idodide
Thyroid storm treatment
PTU +SSKI or Lugols + propranolol + dexamethasone