Migraines

Question 1

Migraine in women before period. Start on NSAID or Triptan when?

Answer 1

2 days before menses and for 5-7 days after

Question 2

If a patient uses acute treatments more than twice per week, or migraine decreases their quality of life, _______can be used

Answer 2

An agent that can decrease migraine frequency. (Antidepressants, anticonvulsants, vitamins, or natural products for at least 2-6 months to decrease frequency by 50%)

Question 3

Triptans can all be repeate how many times?

Answer 3

Once

Question 4

Triptans are CI in ______

Answer 4

Uncontrolled HTN and cerebrovascular disease

Question 5

Which triptans are in a ODT formulation?

Answer 5

Rizatriptan and zolmitriptan

Question 6

Which Triptan are in a NS formulation?

Answer 6

Sumatriptan and zolmitriptan

Question 7

What are the longest acting triptans (slow onset, longer acting)?

Answer 7

Frovatriptan (frova) 26 hour half life

Naratriptan (amerge)

Question 8

________are CI with MAO Is

Answer 8

Initrex, maxalt, and zomig

Question 9

What one is CI with strong 3A4 inhibitors

Answer 9

Relpax

Question 10

Why is valproate prophylaxis avoided in young women with migraines?

Answer 10

Weight gain and can cause PCOS bc of increase in testosterone levels

Question 11

Triptan drugs are _________receptor AGONIST and cause ______of cranial blood vessels

Answer 11

Serotonin (5HT1)

Vasoconstriction