Anticoagukatiob Flashcards
1
Q
________selectively inhibits factor Xa
A
Fondaparinux (Arixtra)
2
Q
_______works by inhibiting Factor Xa
A
Rivaroxaban (Xarelto)
3
Q
What 3 anticoagulants work by binding to anti thrombin III causing a conformational change which increase ATs activity 1,000 fold. AT inactivated thrombin and other proteases involved in blood clotting, including factor Xa
A
UFH
LMWH
Fondaparinux
4
Q
Heparin prophylaxis dose
A
5,000 units SC Q8-12H
5
Q
Heparin antidote
A
Protamine 1mg will reverse 100units of heparin
6
Q
Enoxaparin (Lovenosx) prophylactic dose
A
30 mg SC Q12H or 40mg Sc daily
CrCl
7
Q
List the DTIs
A
Lepirudin (refludan) Arhat robin Bivalirudin (Angiomax) DesiruDin (Ipravask) Dabigatran (Pradaxa)
8
Q
_____is CI if Crcl
A
Fondaparinux
9
Q
Heparin is monitored via ____
A
aPTT every 6 hours until in therapeutic range. Then check daily
10
Q
Can you use tamoxifen and warfarin together?
A
No!
