Thrombosis Revision Flashcards
Usual mechanism behind arterial thrombosis?
Rupture of atherosclerotic plaque
Usual mechanism behind venous thrombosis?
Combination of Virchow’s Triad
Usual location of arterial thrombosis?
Left heart chambers, arteries
Usual location of venous thrombosis?
Venous sinusoids of muscle and valves of veins
Diseases associated with arterial thrombosis?
- Acute coronary syndrome
- Ischaemic stroke
- Claudication
Disease associated with venous thrombosis?
DVT
Composition of arterial thrombi?
Mainly platelets
Composition of venous thrombi?
Mainly fibrin
Treatment for arterial thrombosis?
Anti-platelets: clopidogrel
Treatment for venous thrombosis?
Anti-coagulants: heparin, warfarin
What are the 2 classes of antithrombotic drugs?
- Anticoagulants
2. Antiplatelets
Which antithrombotic drugs are used to treat venous thrombosis?
Anticoagulants
Which antithrombotic drugs are used to treat arterial thrombosis?
Antiplatelets