Theme 4 Crossword - Disorders of Metabolism

Question 1

Condition that results in the accumulation of methionine in the blood?

Answer 1

Homocystinuria

Question 2

Production of this metabolite causes acidification in the body?

Answer 2

Lactic acid

Question 3

Non-protein “helper” molecules that can assist in enzyme catalysed transformations?

Answer 3

Cofactors

Question 4

Steroid hormone involved in renal sodium retention?

Answer 4

Aldosterone

Question 5

Important site of acid-base regulation in the body?

Answer 5

Lungs

Question 6

Hormone that can be used to treat hyperkalaemia?

Answer 6

Insulin

Question 7

The urea cycle primarily takes place in this organ?

Answer 7

Liver

Question 8

Hormone that regulates the body’s retention of water?

Answer 8

ADH

Question 9

An inability to synthesise haem may lead to an accumulation of these metabolites?

Answer 9

Porphyrins

Question 10

An inborn error of metabolism that results in high levels of plasma levels of phenylalanine?

Answer 10

Phenylketonuria

Question 11

Androgen insensitivity syndrome results from a genetic defect in the androgen receptor. Such individuals are genetically…?

Answer 11

Male

Question 12

Congenital hypothyroidism can be treated with?

Answer 12

Thyroxine

Question 13

Decrease in the pH of arterial blood below 7.4?

Answer 13

Acidosis

Question 14

In the organic acidaemia disorder MSUD what do the letters MS stand for?

Answer 14

Maple Syrup

Question 15

Term used to describe a solution with the same electrolyte concentration as normal blood?

Answer 15

Isotonic

Question 16

Form of alkalosis due to hyperventilation?

Answer 16

Respiratory

Question 17

Acidosis can lead to the loss of which electrolyte from cells?

Answer 17

Potassium