Throat Conditions Flashcards
how is neck trauma classified
zones 1-3
what are the investigations of a neck mass
US then FNA to determine tissue type +- MRI for nerve involvement
what is the cause of a laryngeal polyp
laryngeal mucosal reaction to trauma/stress/smoke on cords
what is the difference between a laryngeal polyp and nodule
polyp: unilateral, pedunculated
nodule: young women, bilateral
what is a squamous cell papilloma of the throat and what causes it
benign, HPV type 6 & 11 induce metaplasia of koliocyte cells
what is the presentation of a squamous cell papilloma of the throat
Persistent sore throat, neck mass
what is a paraganglionoma
neuroendocrine paraganglia tumour
what condition is associated with paragangliomas in people under 50yr
MEN2
what is the classification of paraganglionomas
chromaffin +ve or non-chromaffin
what type of paraganglionoma affects the nose/mouth/phayrnx
non-chromaffin
what is a sialolithiasis
salivary gland stone
what is a painful salivary gland in a young person a red flag for
mucoepidermoid carcinoma
what is the commonest salivary gland tumour
benign pleomorphic adenoma of the parotid
what is the management of a benign pleomorphic adenoma of the parotid
excise sine metaplasia risk
what is the pathophysiology of airway obstruction leading to death
resp distress > resp failure > resp arrest > cardiac arrest. Cardio failure > neuro failure
what is stridor
high pitch inspiratory noise due to turbulent airflow
what is the management of airway obstruction
ABC; O2, heliox, CCS, adrenaline
what is the management of burns causing airway obstruction
intubate asap
what investigation should be avoided in airway obstruction
tracheostomy
what are the types of patients who get oral squamous cell carcinoma
young: HPV type 16/18
old smoker/drinker
how does HPV cause squamous cell carcinoma
produce proteins disrupting p53 & RB
where do HPV induced squamous cell carcinomas of the throat occur
oropharynx: tongue base/tonsil
where do alcohol/smoking induced squamous cell carcinomas of the throat occur
vocal cord
what are the investigations of squamous cell carcinoma
biopsy for TNF staging
what is the presentation of HPV SCC
young, lymphadenopathy,
does HPV or alcohol/smoking SCC have a better response to chemotherapy and radiotherpay
HPV induced
what is the 1st step of the WHO pain ladder
non-opioid (e.g. NSAID) +- adjuvant
give examples of NSAIDs
paracetamol, aspirin, ibuprofen
what is an adjuvant analgesic
primary indication not for pain
give examples of adjuvant analgesics
gabapentin, pregabalin, amitriptyline
what is the 2nd step of the WHO pain ladder
mild opioid + non-opioid +- adjuvant
give examples of mild opioids
codeine, co-cocodamol, tramadol
what is the 3rd step of the WHO pain ladder
opioid +- non-opioid +- adjuvant
give examples of moderate-strong opioids
morphine, diamorphine, fentanyl, oxycodone
when should you refer a sore throat from primary care
dysphagia for longer than 3wk, red/white patch/ulcer for longer than 3wk, stridor
how to decide when to give antibiotics for a sore throat
centor criteria
what type of bacteria is diphtheria
cornyebacterium
what is the presentation of diphtheria
very sore throat, grey white membrane on posterior pharynx
what is the treatment of diphtheria
antitoxin + penicillin/erythromycin
what type of vaccine is the diphtheria vaccine
toxoid
what is a risk factor for oral thrush
CCS inhaler
what is the infecting organism in oral thrush
candida albicans
what is the treatment of oral thrush
nystatin
what is paramyoxovirus
mumps; bilateral parotid salivary gland infection
what are complications of mumps
meningitis, male infertility
what is the infecting organism in primary syphilis
treponema pallidum
what is an aphthous ulcer
round recurrent self limiting mouth ulcers without infection/systemic disease
what virus causes hand foot and mouth
coxsackie enterovirus
what is the presentation of hand foot and mouth disease
pyrexic, anorexia, leg ache, itchy papules on hand, foot and mouth
what is the transmission of hand, foot and mouth
faecal-oral
how is hand, foot and mouth diagnosed
clinical Dx or swab in viral transport medium for pcr
what is the management of hand, foot and mouth
self limiting, fluids, NSAID, hand-washing
what is the infecting organism in herpangina
enterovirus coxsackie
what is the presentation of herpangina
ulcers on the soft palate of a child
what is the management of herpangina
self-limiting
what is herpetic whitlow
herpes simplex infection on finger, often dentist/ anaesthetist
how is HSV1 transmissed
saliva
how is HSV1 infection diagnosed
clinical or swab virus in transport medium for viral DNA PCR
what is the management of active HSV1 infection
acyclovir
what is a complication of HSV1
encephalitis
what type of herpes causes oral lesions
type 1 (i think?)
what is primary gingivostomatitis
primary HSV1 infection in young child causing ulcer plus systemic upset
what are the commonest infecting organisms in tonsillitis
viruses: rhinovirus / influenza / enterovirus / adenovirus. rarely EBV
which bacteria can cause tonsillitis
h. influenzae, s. pyogenes, s. aureus, s. pneumoniae
which tonsil inflam will cause AOM
pharyngeal
what is the difference in the presentation of viral and bacterial tonsillitis
viral no fever
bacterial lymphadenopathy
bacterial odynophagia & halitosis
bacterial lasts longer
what is the commonest bacteria causing tonsillits
s. pyogenes
what are the complications of s. pyogenes tonsillits
rheumatic fever, glomerulonephritis
what are the infection control precautions for s. pyogenes tonsillits
SICPS+ contact +- droplet precautions
how to decide whether to give antibiotics for tonsillits
centor criteria
how to do the centor criteria
one point for: fever no cough tonsillar exudate tender anterior cervical LN <15yr - one point if >45yr
do you give antibiotics for a centor criteria score of 0-1
no
do you give antibiotics for a centor criteria score of 2-3
if symptoms progress
do you give antibiotics for a centor criteria score of 4-5
start empirical ABx
what antibiotics can be prescribed for tonsillitis
1st penicillin
2nd clarithromycin
when is surgery indicated for tonsillitis
episodes prevent ADL + 5+ in past 2yr given ABx OR 3 in past 1yr given ABx
what is the commonest complication of tonsillitis
quinsy
what is quinsy
unilateral peritonsillar abscess
what is the presentation of quinsy
odynophagia, trismus, tonsil/uvula medial displacement
what is the management of quinsy
aspirate + ABx
what is the infecting organism in glandular fever aka infectious mononucleosis
epstein barr virus
what is seen on examination in glandular fever
enlarged tonsils + exudate, cervical lymphadenopathy, +- jaundice, +- rash, +- palatal petechiae, +- hepatosplenomegaly
what would the patient complain of in glandular fever
fever, sore throat, malaise
what is diagnostic of glandular fever
EBV IgM (not IgG since could have had childhood infection)
what investigations can be done for glandular fever
FBC, LFT, serology, blood film, Paul Bunnel, Monospot heterophile Ab, CRP
what is seen on a blood film in glandular fever
large atypical lymphocytes plus leukocytosis
what is the management of glandular fever
self limiting over 2-4weeks
what drug shouldn’t be prescribed for glandular fever and why
amoxicillin causes macular rash
what is the management of glandular fever if its causing anaemia or tonsillitis
CCS
what are complications of glandular fever
anaemia, spleen rupture, lymphoma, thrombocytopaenia