Throat Conditions Flashcards
how is neck trauma classified
zones 1-3
what are the investigations of a neck mass
US then FNA to determine tissue type +- MRI for nerve involvement
what is the cause of a laryngeal polyp
laryngeal mucosal reaction to trauma/stress/smoke on cords
what is the difference between a laryngeal polyp and nodule
polyp: unilateral, pedunculated
nodule: young women, bilateral
what is a squamous cell papilloma of the throat and what causes it
benign, HPV type 6 & 11 induce metaplasia of koliocyte cells
what is the presentation of a squamous cell papilloma of the throat
Persistent sore throat, neck mass
what is a paraganglionoma
neuroendocrine paraganglia tumour
what condition is associated with paragangliomas in people under 50yr
MEN2
what is the classification of paraganglionomas
chromaffin +ve or non-chromaffin
what type of paraganglionoma affects the nose/mouth/phayrnx
non-chromaffin
what is a sialolithiasis
salivary gland stone
what is a painful salivary gland in a young person a red flag for
mucoepidermoid carcinoma
what is the commonest salivary gland tumour
benign pleomorphic adenoma of the parotid
what is the management of a benign pleomorphic adenoma of the parotid
excise sine metaplasia risk
what is the pathophysiology of airway obstruction leading to death
resp distress > resp failure > resp arrest > cardiac arrest. Cardio failure > neuro failure
what is stridor
high pitch inspiratory noise due to turbulent airflow
what is the management of airway obstruction
ABC; O2, heliox, CCS, adrenaline
what is the management of burns causing airway obstruction
intubate asap
what investigation should be avoided in airway obstruction
tracheostomy
what are the types of patients who get oral squamous cell carcinoma
young: HPV type 16/18
old smoker/drinker
how does HPV cause squamous cell carcinoma
produce proteins disrupting p53 & RB
where do HPV induced squamous cell carcinomas of the throat occur
oropharynx: tongue base/tonsil
where do alcohol/smoking induced squamous cell carcinomas of the throat occur
vocal cord
what are the investigations of squamous cell carcinoma
biopsy for TNF staging
what is the presentation of HPV SCC
young, lymphadenopathy,
does HPV or alcohol/smoking SCC have a better response to chemotherapy and radiotherpay
HPV induced
what is the 1st step of the WHO pain ladder
non-opioid (e.g. NSAID) +- adjuvant
give examples of NSAIDs
paracetamol, aspirin, ibuprofen
what is an adjuvant analgesic
primary indication not for pain
give examples of adjuvant analgesics
gabapentin, pregabalin, amitriptyline
what is the 2nd step of the WHO pain ladder
mild opioid + non-opioid +- adjuvant
give examples of mild opioids
codeine, co-cocodamol, tramadol
what is the 3rd step of the WHO pain ladder
opioid +- non-opioid +- adjuvant
give examples of moderate-strong opioids
morphine, diamorphine, fentanyl, oxycodone
when should you refer a sore throat from primary care
dysphagia for longer than 3wk, red/white patch/ulcer for longer than 3wk, stridor
how to decide when to give antibiotics for a sore throat
centor criteria