THORACIC Section 5: LUNG CANCER Flashcards

1
Q

A solitary pulmonary nodule (SPN) is defined as?

A
  1. Oval lesion
  2. < 3 cm
  3. Needs to be surrounded by lung parenchyma
  4. No associated adenopathy or pleural effusion
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2
Q

What are the 4 classic “benign calcification” patterns?

A
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3
Q

What calcification pattern is considered the most suspicious?

A

“eccentric pattern”

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4
Q

Popcorn and central calcifications are benign except in the setting of what disease?

A

GI cancer

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5
Q

Solid calcifications are benign except in what disease?

A

Osteosarcoma

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6
Q

Benign or Malignant?

Air Bronchogram through the nodules

A

Malignant.

usually Adenocarcinoma in situ

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7
Q

Benign or Malignant?

Spiculated Margins “Corona Radiata Sign”

A

Malignant

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8
Q

Benign or Malignant?

Partially solid lesions with ground-glass component

A

Malignant

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9
Q

Benign or Malignant?

Presence of Fat

A

Benign

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10
Q

Benign or Malignant?

Rapid Doubling Time (less than 1 month)

A

Benign

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11
Q

Slow Doubling Time (longer than 16 months) *Stable at two years

A

Benign

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12
Q

Describe ground glass vs Consolidative

A

Ground Glass (GG) opacity is defined by preserved bronchial and vascular markings.

Consolidative (C) opacities will obscure the bronchial and vascular markings.

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13
Q

What is the moist suspicious morphology that you can have in a Solitary pulmonary nodule?

A

A part solid with a ground glass component

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14
Q

PET for SPN: Cancer vs Not Cancer

Solid Nodule (>1cm in size):
Hot = ?, COLD = ?

Ground Glass Nodules:
Hot = ?
COLD = ?

A

PET for SPN: Cancer vs Not Cancer

Solid Nodule (>1cm in size):
Hot = Cancer , COLD = Not Cancer

Ground Glass Nodules:
Hot = infectionn
COLD = CANCER

Solid noduel = HOT
GGO = COLD

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15
Q

70% of Lung CA is in the ___ Lobes

A

upper

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16
Q

Peripheral basilar cancer is more common in what condition?

A

Pulmonary fibrosis

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17
Q

SPN in the stting of head and neck CA is more likely to be a ?

A

Primary bronchogenic CA

18
Q

Screening CT minimum size thickness

19
Q

The most commonly encounter “risk” of lung CA

A

False positive

20
Q

Growth is considdered __ mm or more in 1 year

21
Q

LUNG RADS Category

Negative, < 1% chance of CA. Either no nodules or granulomas

Follow up in?

A

Category 1, 1 year follow up

22
Q

LUNG RADS Category

Benign < 1 % change of CA.
Baseline exam - Nodules smaller thant 6 mm.
Subsequent exam - No new nodules larger than 4 mm.
Ground glass nodule smaller thant 30 mm.
Perifissural nodules < 10 mm

Ff up in?

A

Category 2

Follow up in 1 year

23
Q

Probably Benign, 1-2%. chance of CA.
Baseline nodule 6-8 mm.
Subsequent exam new nodule >4mm.
Ground glass >30 mm

A

Category 3

6 month follow-up

24
Q

LUNG RADS Category

Suspicious, 5-15% chance of CA
Baseline 8-15 mm
New nodule 6-8 mm

Follow-up?

A

Category 4a

3 months follow up vs PET

25
LUNG RADS Category Suspicious, >15% chance of CA > 15 mm at baseline New nodule >8 mm
Category 4b PET vs Tissue Sampling
26
LUNG RADS Category >15% chance of CA Worsening of category 3 or 4 nodules (growth or new spiculation
Category 4x PET vs tissue sampling
27
Fleischner Guidelines only apply on patients who are?
Older than 35 No known or suspected CA Not immunocompomised
28
Nodule characterization should be performed on thin-slic CT images ___mm
< or = 1.5 mm.
29
Fleishner Society Overview for SOLID nodules < 6mm, Single, Low Risk
No follow up
30
Fleishner Society Overview for SOLID nodules <6mm Single High Ristk
Optional CT at 12 months
31
Fleishner Society Overview for SOLID nodules < 6mm Multiple Low Risk
No follow up
32
Fleishner Society Overview for SOLID nodules <6mm Multiple High Risk
CT 12 months - optional
33
Fleishner Society Overview for SOLID nodules 6-8 mm Single Low risk
CT 6-12 month follow-up Consider CTR at 18-24
34
Fleishner Society Overview for SOLID nodules 6-8 mm Single High risk
CT 6-12 month follow-up Then CT at 18-24
35
Fleishner Society Overview for SOLID nodules 6-8 mm Multiple Low risk
CT 3-6 months hen Consider CT at 18-24
36
Fleishner Society Overview for SOLID nodules 6-8 mm Multiple High risk
CT 3-6 months, then CT at 18-24
37
Fleishner Society Overview for SOLID nodules >8 mm Single Low and High risk
Consider CT at 3 mo, PET/CT or Biopsy
38
Fleishner Society Overview for SOLID nodules >8 mm Multiple Low risk
Consider CT at 3 mo, PET/CT or Biopsy
39
Fleishner Society Overview for SOLID nodules >8 mm Multiple High risk
CT at 3-6 months, then CT at 18-24 months
40
Tumor that causes the associated syndrome (shoulder pain, C8-T2 radiculopathy, and Horner syndrome)
Superior sulcus / Pancoast Tumor
41
ptosis (lazy eyelid) + miosis (tiny pupil)
Horner syndrome