THORACIC Section 5: LUNG CANCER Flashcards

1
Q

A solitary pulmonary nodule (SPN) is defined as?

A
  1. Oval lesion
  2. < 3 cm
  3. Needs to be surrounded by lung parenchyma
  4. No associated adenopathy or pleural effusion
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2
Q

What are the 4 classic “benign calcification” patterns?

A
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3
Q

What calcification pattern is considered the most suspicious?

A

“eccentric pattern”

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4
Q

Popcorn and central calcifications are benign except in the setting of what disease?

A

GI cancer

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5
Q

Solid calcifications are benign except in what disease?

A

Osteosarcoma

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6
Q

Benign or Malignant?

Air Bronchogram through the nodules

A

Malignant.

usually Adenocarcinoma in situ

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7
Q

Benign or Malignant?

Spiculated Margins “Corona Radiata Sign”

A

Malignant

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8
Q

Benign or Malignant?

Partially solid lesions with ground-glass component

A

Malignant

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9
Q

Benign or Malignant?

Presence of Fat

A

Benign

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10
Q

Benign or Malignant?

Rapid Doubling Time (less than 1 month)

A

Benign

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11
Q

Slow Doubling Time (longer than 16 months) *Stable at two years

A

Benign

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12
Q

Describe ground glass vs Consolidative

A

Ground Glass (GG) opacity is defined by preserved bronchial and vascular markings.

Consolidative (C) opacities will obscure the bronchial and vascular markings.

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13
Q

What is the moist suspicious morphology that you can have in a Solitary pulmonary nodule?

A

A part solid with a ground glass component

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14
Q

PET for SPN: Cancer vs Not Cancer

Solid Nodule (>1cm in size):
Hot = ?, COLD = ?

Ground Glass Nodules:
Hot = ?
COLD = ?

A

PET for SPN: Cancer vs Not Cancer

Solid Nodule (>1cm in size):
Hot = Cancer , COLD = Not Cancer

Ground Glass Nodules:
Hot = infectionn
COLD = CANCER

Solid noduel = HOT
GGO = COLD

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15
Q

70% of Lung CA is in the ___ Lobes

A

upper

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16
Q

Peripheral basilar cancer is more common in what condition?

A

Pulmonary fibrosis

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17
Q

SPN in the stting of head and neck CA is more likely to be a ?

A

Primary bronchogenic CA

18
Q

Screening CT minimum size thickness

A

2.5 mm

19
Q

The most commonly encounter “risk” of lung CA

A

False positive

20
Q

Growth is considdered __ mm or more in 1 year

A

1.5 mm

21
Q

LUNG RADS Category

Negative, < 1% chance of CA. Either no nodules or granulomas

Follow up in?

A

Category 1, 1 year follow up

22
Q

LUNG RADS Category

Benign < 1 % change of CA.
Baseline exam - Nodules smaller thant 6 mm.
Subsequent exam - No new nodules larger than 4 mm.
Ground glass nodule smaller thant 30 mm.
Perifissural nodules < 10 mm

Ff up in?

A

Category 2

Follow up in 1 year

23
Q

Probably Benign, 1-2%. chance of CA.
Baseline nodule 6-8 mm.
Subsequent exam new nodule >4mm.
Ground glass >30 mm

A

Category 3

6 month follow-up

24
Q

LUNG RADS Category

Suspicious, 5-15% chance of CA
Baseline 8-15 mm
New nodule 6-8 mm

Follow-up?

A

Category 4a

3 months follow up vs PET

25
Q

LUNG RADS Category

Suspicious, >15% chance of CA
> 15 mm at baseline
New nodule >8 mm

A

Category 4b

PET vs Tissue Sampling

26
Q

LUNG RADS Category

> 15% chance of CA
Worsening of category 3 or 4 nodules (growth or new spiculation

A

Category 4x

PET vs tissue sampling

27
Q

Fleischner Guidelines only apply on patients who are?

A

Older than 35
No known or suspected CA
Not immunocompomised

28
Q

Nodule characterization should be performed on thin-slic CT images ___mm

A

< or = 1.5 mm.

29
Q

Fleishner Society Overview for SOLID nodules

< 6mm, Single, Low Risk

A

No follow up

30
Q

Fleishner Society Overview for SOLID nodules

<6mm
Single
High Ristk

A

Optional CT at 12 months

31
Q

Fleishner Society Overview for SOLID nodules

< 6mm
Multiple
Low Risk

A

No follow up

32
Q

Fleishner Society Overview for SOLID nodules

<6mm
Multiple
High Risk

A

CT 12 months - optional

33
Q

Fleishner Society Overview for SOLID nodules

6-8 mm
Single
Low risk

A

CT 6-12 month follow-up

Consider CTR at 18-24

34
Q

Fleishner Society Overview for SOLID nodules

6-8 mm
Single
High risk

A

CT 6-12 month follow-up

Then CT at 18-24

35
Q

Fleishner Society Overview for SOLID nodules

6-8 mm
Multiple
Low risk

A

CT 3-6 months hen Consider CT at 18-24

36
Q

Fleishner Society Overview for SOLID nodules

6-8 mm
Multiple
High risk

A

CT 3-6 months, then CT at 18-24

37
Q

Fleishner Society Overview for SOLID nodules

> 8 mm
Single
Low and High risk

A

Consider CT at 3 mo, PET/CT or Biopsy

38
Q

Fleishner Society Overview for SOLID nodules

> 8 mm
Multiple
Low risk

A

Consider CT at 3 mo, PET/CT or Biopsy

39
Q

Fleishner Society Overview for SOLID nodules

> 8 mm
Multiple
High risk

A

CT at 3-6 months, then CT at 18-24 months

40
Q

Tumor that causes the associated syndrome (shoulder pain, C8-T2 radiculopathy, and Horner syndrome)

A

Superior sulcus / Pancoast Tumor

41
Q

ptosis (lazy eyelid) + miosis (tiny pupil)

A

Horner syndrome