THORACIC Section 5: Adenocarcinoma In-Situ Spectrum

Question 1

Adenocarcinoma In-Situ Spectrum is formerly known as?

Answer 1

Bronchoalveolar CA

Question 2

What are the two pre-invasive Subtypes?

Answer 2

Atypical Adenomatous Hyperplasia of the Lung (AAH)

and

Adenocarcinoma in Situ (ACIS)

Question 3

The smaller (< 5mm) and more mild pre-invasive sub-type.
Usually a pure ground glass nodule.

Answer 3

Atypical Adenomatous Hyperplasia of the Lung (AAH)

Question 4

Typically larger than AAH but < 3 cm. Although features
overlap with AAH, they tend to be more part-solid (rather
than pure ground glass)

Answer 4

Adenocarcinoma in situ (ACIS)

Question 5

What are the two INVASIVE subtypes?

Answer 5

Minimally Invasive Adenocarcinoma (MIA)

and

Invasive Mucinous Adenocarcinoma

Question 6

These are also < 3 cm. The distinction is that there is < 5
mm of stromal invasion ( > 5 mm will be called a lepidic
predominant adenocarcinoma).

Answer 6

Minimally Invasive Adenocarcinoma
(MIA)

Question 7

This is what most people used to call BAC
(bronchoalveolar carcinoma).

Answer 7

Invasive Mucinous Adenocarcinoma