THORACIC Section 11: Alveolar Flashcards

1
Q

Condition where surfactant accumulates in the alveoli and terminal bronchioles.

A

Pulmonary Alveolar Proteinosis (PAP)

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2
Q

Secondary causes of Pulmonary Alveolar Proteinosis (PAP)

A

Cancer or inhilation (Silico-proteinosis)

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3
Q

Pulmonary Alveolar Proteinosis are at increased risk of what infection?

A

Nocardia. Can have Nocardia brain abscess.

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4
Q

PAP associated disease in children (<age 1)

A

Alymphoplasia

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5
Q

Describe the pattern and areas involved

A

Interlobular septal thickening and ground glass.
Typically central and symmetric, sparing the apices and costophrenic angles

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6
Q

Causes of crazy paving appearance

A

C - COPD/Cancer/COVID
R - Respiratory distress (Acute)
A - Alveolar proteinosis
Z - Zipper (Lipoid pneumonia, So fat you cannot zip your pants)
Y - Y are you hemorrhageing? hahaha! -
P aving - PCP

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7
Q

Describe the pattern

A

Interlobar septal thickening with GG

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8
Q

CT scan appearance of Lipoid pneumonia

A

Low attenuation/fat density in the consolidation.

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9
Q

Results from post obstructive process (cancer) causing build up of lipid laden macrophages

A

Endogenous Lipoid pneumonia

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10
Q

Diagnosis?
Describe

A

Lipoid pneumonia
Fat Density in the consolidation

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11
Q

When showed soft tissue window on lung CT, always think about these things!

A

fat lesion - think hamartoma or lipoid pneumonia

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12
Q

When showed BONE window on lung CT, always think about these things!

A

Pulmonary microlithiasis.

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13
Q

It’s not an active infection (as the name would suggest) but instead granulation tissue deposition within the alveolar spaces secondary to fibroblast proliferation.

A

Organizing Pneumonia

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14
Q

Antibiotics wont work in this type of pneumonia. Respond well to steroids.

A

Organizing pneumonia

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15
Q

Diagnosis?
Describe the pattern

A

Cryptogenic Organizing pneumonia

Reverse Halo

Patchy air space consolidation or GGO (90%), in a peripheral or peri-bronchial distribution (sometimes a perilobular/arcade-like pattern).

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15
Q

Name conditions presenting as peripheral consolidations

A

Organizing pneumonia

16
Q

Consolidation around a ground glass center.

A

Reverse Halo (Atoll) Sign

17
Q

Classic sign of Oganizing Pneumonia

A

REverse Halo (Atoll) Sign

18
Q

Conditions were Reverse Halo Sign is seen

A

COVID
Organizing pneumonia

19
Q

Describe?
Diagnosis?

A

Classic Look on CXR:
* Bilateral
* Non-segmental Consohdation
* Favoring the outer 2/3 o f the lungs (peripheral)

Eosinophilic Pneumonia

20
Q

CT Findings of Chronic Eosinphilic Pneumonia

A

Peripheral GGO or consolidation.
Upper lobes tend to be favored.

21
Q

Name this pneumonia

Can be idiopathic or associated with a known antigen. Peripheral eosinophilia (blood test) is usually present. An asthma history is found in about 50% of cases. It looks exactly like COP (both can present as peripheral consolidations). When you say COP you should say this one too (some people think it’s the same disease as COP).

A

Chronic Eosinophilic Pneumonia

22
Q

HALO SIGNS:

-Nodule with ground glass around it
-Represents hemorrhage / invasion into surrounding tissues

A

Halo

23
Q

SIGNS:

Central ground glass with rim of consolidation

A

Reverse HALO (Atoll)

24
Q

Halo sign is seen in what conditions?

A
  • Invasive Aspergillosis (Classic)
  • Other Fungus
  • Hemorrhagic Mets
  • Adenocarcinoma in Situ (BAC)
  • Wegeners
25
Q

Reverse Halo (Atoll) Sign is seen in what conditions?

A

Cryptogenic Organizing Pneumonia (CLASSIC)
COVID
TB
Pulmonary Infarct
Invasive Fungal and Wegeners
** these can also be seen with regular Halo - COVID

26
Q

This is actually common. It’s caused by inhaled organic antigens. It has acute, subacute, and chronic stages. Most o f the time it’s imaged in the subacute stage.

A

Hypersensitivity Pneumonitis

27
Q

Patchy ground glass opacities. Ill-defined Centrilobular ground glass nodules (80%). Often has mosaic perfusion, and air trapping.

A

Subacute Hypersensitivity Pneumonitis

28
Q

Looks like UIP + Air trappins. You are gonna have traction bronchiectasis and air trapping.

A

Chronic Hypersensitivity Pneumonitis

29
Q

Diagnosis?
Describe

A

Hypersensitivity pneumonitis
Headcheese
Juxtaposition of 3 different regions
Groundglass + Air Trapping + Normal Lungs

30
Q

Explanation of Headcheese apperance of Hypersensitivity pneumonitis

A

Infiltrative process (ground glass)
Obstructive process (mosaic attenuation / air-trapping)