Thiazide diuretics Flashcards
1
Q
What do these inhibits?
A
Na2+ reabsorption at the beginning of DCT -> blocks thiazide sensitive Na-Cl symporter
2
Q
What is lost as a result of more Na2+ reaching the collecting ducts?
A
K+
3
Q
What are some examples?
A
- furosemide
- bendroflumethiazide
4
Q
What is bendroflumethazide used to manage?
A
hypertension
5
Q
What are the side effects of thiazide diuretics?
A
- dehydration
- postural hypertension
- hyponatraemia, hypokalaemia, hypercalcaemia
- gout
- impaired glucose tolerance
- impotence
