Amiodarone Flashcards
1
Q
What class of agent is amiodarone?
A
class III antiarrhythmic agent
2
Q
What is amiodarone used in?
A
atrial, nodal and ventricular tachycardia
3
Q
What does amiodarone block?
A
K+ channels - inhibiting repolarisation and prolonging action potential
4
Q
What is the class I effect of amiodarone?
A
blocks Na2+ channels
5
Q
How is amiodarone monitored?
A
- TFT, LFT, U&E, CXR prior to treatment
- TFT, LFT every 6 months
6
Q
What are the adverse effects of amiodarone?
A
- hypo & hyperthyroidism
- pulmonary fibrosis/pneumonitis
- liver fibrosis/hepatitis
- ‘slate-grey’ appearance
- bradycardia
- lengthens QT interval
