Statins Flashcards

1
Q

What do statins inhibit?

A

HMG-CoA reductase

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2
Q

What are the side effects of statins?

A
  • myopathy: myalgia, myostis
  • liver impairment
  • inc. risk of intracerebral haemorrhage in patients who have had a previous stroke
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3
Q

What are the contraindications of statins?

A
  • macrolides (erythromycin, clarithromycin) - statins stopped until cycle of macrolides complete
  • pregnancy
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