Statins Flashcards
1
Q
What do statins inhibit?
A
HMG-CoA reductase
2
Q
What are the side effects of statins?
A
- myopathy: myalgia, myostis
- liver impairment
- inc. risk of intracerebral haemorrhage in patients who have had a previous stroke
3
Q
What are the contraindications of statins?
A
- macrolides (erythromycin, clarithromycin) - statins stopped until cycle of macrolides complete
- pregnancy