Adenosine Flashcards
1
Q
What is adenosine most used in?
A
supraventricular tachycardia (SVT)
2
Q
What enhances adenosine effects?
A
dipyridamole (antiplatelet)
3
Q
What blocks the effects of adenosine?
A
theophyllines
4
Q
What patients should adenosine be avoided in?
A
asthmatics
5
Q
What does adenosine cause in the AV node?
A
transient heart block
6
Q
What receptor is adenosine an agonist of?
A
A1 receptor
7
Q
What happens when adenosine acts on the A1 receptor in the AV node?
A
- inhibits adenylyl cyclase
- reduces cAMP & causing hyperpolarisation by increasing outward K+ influx
8
Q
What should adenosine be infused with?
A
large-calibre cannula
9
Q
What are the adverse effects of adenosine?
A
- chest pain
- bronchospasm
- transient flushing
- enhance conduction down accessory pathway (inc. ventricular rate)
