Thiamine (Vitamin B1)

Question 1

THIAMINE (VITAMIN B1)

Pharmacology & Actions

Answer 1

• Required for carbohydrate metabolism, converts glucose into energy
• Chronic alcohol intake interferes with the absorption, intake, and utilization of thiamine
• Patients who are malnourished, or have chronic alcohol abuse, may develop Wernicke’s encephalopathy if given IO/IV glucose without concomitant administration of thiamine

Question 2

THIAMINE (VITAMIN B1)

Indications

Answer 2

• Thiamine should precede the administration of Dextrose or Glucagon in any adult patient if there is any evidence of malnutrition or alcohol abuse

Question 3

THIAMINE (VITAMIN B1)

Absolute Contraindications

Answer 3

• Thiamine allergy

Question 4

THIAMINE (VITAMIN B1)

Precautions & Side Effects

Answer 4

• None in prehospital setting

Question 5

THIAMINE (VITAMIN B1)

Administration

Answer 5

• IV/IO
• Onset: Hours
• Peak Effect: 3-5 days
• Duration: Unknown