Midazolam (Versed)

Question 1

MIDAZOLAM (VERSED)

Pharmacology & Actions

Answer 1

• Benzodiazepine that functions as a CNS depressant, anticonvulsant, and sedative

Question 2

MIDAZOLAM (VERSED)

Indications

Answer 2

• Seizures
• Sedation
• Agitation/excited delirium
• Uncontrolled shivering in hyperthermia

Question 3

MIDAZOLAM (VERSED)

Absolute Contraindications

Answer 3

• Respiratory and/or CNS depression
• Midazolam (versed) allergy

Question 4

MIDAZOLAM (VERSED)

Precautions & Side Effects

Answer 4

• Midazolam has more potential than the other IV benzodiazepines to cause respiratory depression. Respiratory depression and/or hypotension can occur, the patient should be monitored closely
• Most likely to produce respiratory depression in patients who have taken other depressant drugs, especially alcohol and barbiturates, or when given rapidly
• Elderly patients may have more profound respiratory and/or CNS depression, half dose should be administered

Question 5

MIDAZOLAM (VERSED)

Administration

Answer 5

• IV/IN
  
  • Onset: Immediate
  • Peak Effect: 3-5min
  • Duration: <2 hours
• IM
  
  • Onset: 15min
  • Peak Effect: 30-60min
  • Duration: 1-6 hours