Sodium Bicarbonate

Question 1

SODIUM BICARBONATE

Pharmacology & Actions

Answer 1

• Sodium bicarbonate reacts with hydrogen ions, forming water and carbon dioxide, correcting metabolic acidosis
• Increases blood and urinary pH by releasing a bicarbonate ion, which in turn neutralizes hydrogen ion concentrations

Question 2

SODIUM BICARBONATE

Indications

Answer 2

• Cardiac arrest when hyperkalemia or tricyclic antidepressant (TCA) overdose is suspected
• Tricyclic antidepressant overdose
• Extremity trauma, crush syndrome

Question 3

SODIUM BICARBONATE

Absolute Contraindications

Answer 3

• Sodium bicarbonate allergy

Question 4

SODIUM BICARBONATE

Precautions & Side Effects

Answer 4

• Administration of sodium bicarbonate may result in metabolic alkalosis, which may be difficult to reverse

Question 5

SODIUM BICARBONATE

Administration

Answer 5

• IV/IO
• Onset: Immediate
• Peak Effect: < 15min
• Duration: 1-2hrs