Therapeutic Uses of Direct Acting Sympathomimetics or Sympatholytics

Question 1

Sympathomimetics vs/ lyitcs

Answer 1

Lytics will prevent

Mimetics will activate

Question 2

NE and septic shock

Answer 2

Used to increase systemic arterial blood pressure in septick shock by stimulating alpha1-adrenergic receptors

Question 3

NE on alpha 1 and beta 1

Answer 3

Alpha 1 - vasoconstriction
Beta 1 - positive inotropic

Increases cardiac output and would be effective in cardiogenic shock

Question 4

Pseudoephedrine

Answer 4

Mimetic used in cold prep

Constricts nasal mucosa and blood vessels leading to decreased resistance to air flow

Alpha 1 mediated

Question 5

Pseduophedrine side effects

Answer 5

Increased BP and insomnia

Question 6

Pseudophedrine drug interactions

Answer 6

MAOIs, TCAs or amphetamines

Question 7

Mydriatic effects

Answer 7

Alpha 1 agonists can be used to produce mydriasis

Question 8

Epineprhine and albuterol

Answer 8

Beta 2 adrenergic mimetics

Still work on Beta 1 but prefer beta 2…activate cellular processes using cAMP

Question 9

Activation of beta 2 results in

Answer 9

Bronchodilation and increase in airway resistance

Question 10

Epineprhine

Answer 10

Beta 2 agonist to tx respiratory distress or bronchospasm (asthma or allergic reactions)

Question 11

Beta 1 target use

Answer 11

Can help provide inotropic support to patients with decompensated herat failure

Question 12

Neuro uses of beta blockers

Answer 12

Glaucoma (timolo)
Migraine
Performance anxiety
Essential tremor

Question 13

Neuro side effects of beta blockers

Answer 13

Fatigue, depression, drowsiness