Practical Anesthetic Pharmacology

Question 1

ASA Status

Answer 1

1 - normal
2 - mild dz with no functional limitations 
3 - some functional limitations 
4 - disease is constnt threat to life 
5 - not expected to survive
6 - brain dead

Question 2

Preop anxiolysis

Answer 2

THink Benzodiazepines with short onset and duration that also privdes amnesia

Question 3

Risk of PONV

Answer 3

Female gender
Non smoker
Previous Hx
Post op opiate

25% for each

Question 4

How to tx PONV

Answer 4

Serotonin antagonists (5HT3)
Dexamethasone
Scopolamine
Totl IV anesthetic (probably propofol)

Question 5

Purpose of test dose and what to look for

Answer 5

Make sure it is not in bad place

Give lidocaine with epinephrine

Will make HR increase or perioral numbeness if in veseels

If in SA space, then T6-8 block

Question 6

Most common inductor of anesthesia

Answer 6

Propofol

Question 7

MAC of various agents

Answer 7

Desflurane - 6
Sevoflurane - 1.7
Isoflurane - 1.17
N2O - 105

MACs is concentration that 1/2 of patients won’t move

MACs are additive

Shoot for 1.3-1.4 the MAC

Question 8

Mech of termination of inhalation

Answer 8

Vaporizer turned off and partial pressure of desflurane drops in alveolus and gas moves from the braqin to the blood to the alveolus and is exhaled