Theme 6 Flashcards
Signal Transmission in the Nervous System
Neurons use electrical signals to communicate with:
neurons
muscles
glands
electrical signals or nerve impulses involve changes in the amount of electrical charges across a cell’s plasma membrane. This is called:
Membrane Potentials
T of F: All cells have membrane potentials.
True. But only neurons, muscle, and endocrine cells are excitable.
what types of cells are excitable?
endocrine
muscle
neuron
Why do we study squid axons?
Squid giant axons are used extensively to study membrane potentials.
What is the diameter of a typical giant axon of a squid?
1mm
what is the function of the giant axon of a squid?
controls part of the water jet propulsion.
Is the giant axon of a squid myelinated or unmyelinated?
unmyelinated; which decreases the conduction velocity potential substantially.
What decreases the conduction velocity potential of a squid giant axon?
it being unmyelated.
Voltmeter does what?
- records the voltage difference between the micro electrodes inside and outside the neuron.
- measure of membrane potential
- measurement made as a function of time.
T or F: Neurons are electrically Polarized
True; outside of the membrane and inside of the membrane is polarized.
The positive and negative “poles” of a neuron are…
on the inside and outside of the cell membrane.
What acts as a barrier that separates the charges within a neuron?
the plasma membrane
The difference in charges on the inside and outside of a cell membrane act as :
an electrical force measured in volts.
T or F : The plasma membrane is permeable to cation and anions
False - impermeable to cations and anions.
plasma membrane of a Neuron functions as:
- separates charge (on inside and outside of cell)
- maintains resting potential within cell. (-70mV)
- Negative ions within the cell are drawn to the positive ions arrayed on the outside surface of the membrane.
The resting potential inside the cell:
-70mV
Which is more negative? The interior of the neuron cell membrane or the exterior?
interior cell membrane
What type of channels do Ions move through?
gated channels.
what are the two types of gated channels?
Voltage-gated
Ligand-gated
Voltage gated channel
open and close in response to voltage changes
ligand gated channels
open and close in response to ligands or chemicals.
What are the 3 membrane factors that contribute to resting potential?
- Na+/K+ -ATPase pump
- Ion channels
- Negatively charged molecules such as proteins more abundant inside the cell.
Na+/K+-ATPase pump
transports 3 Na+ out for every 2K+ moved in.
Do ion channels need energy?
No.
Two types of Ion channels that contribute to resting potential?
Na+ specific channels
K+ specific channels
Ion channels
allows passive movement of ions
Within a neuron cell membrane, there are more ungated channels of which type? K+ or Na+
more K+ ungated channels than Na+ ungated channels
Neural membrane is more permeable to which ion at rest? K+ or Na+?
K+
What are the 3 possible states of sodium channels?
- Open
- Closed
- Inactive
There are more K+ or Na+ in the cell?
K+
There are more K+ or Na+ outside the cell?
Na+
Membrane potential
the difference between the electric charges inside and outside the cell.
Resting Potential
membrane potential of a cell that is not sending nerve impulses
Action potential
membrane potential of a cell that is sending nerve impulses