Theme 10 Flashcards
VDCC Voltage dependent calcium channel
cell membrane ion channels with a permeability to the ion Ca2+
when do VDCC open?
depolarized membrane potentials in excite able cells.
What kinds of cells are excitable?
muscle
glial
neurons
Activation of VDCC’s allows Ca2+ entry into the cell resulting in:
muscle contraction
excitation of neurons
up-regulation of gene expression
release of hormones or neurotransmitters
Glutamate
the carboxylate anions and salts of the non-essential amino acid glutamic acid
What is the most abundant excitatory neurotransmitter in the vertebrate nervous system?
glutamate
Glutamate Receptors are _____ - ______ channels that make the cell to be voltage-dependent
sodium-calcium
Synaptic plasticity
a cellular mechanism for learning and memory
What is critical in synaptic plasticity?
Ca2+ flux through the glutamate receptor
Single lens eye are found in what type of animals?
founds in vertebrates, some mollusks (squid ect) and in some snails and annelids (worms?)
Sclera
strong outer white sheath
Cornea
continuous with sclera but thin and clear
Aqueous humor
anterior cavity that holds thin fluid
Vitreous humor
posterior cavity that holds thick fluid (maintains eye shape)
Iris
pigmented smooth muscle controlling size of pupil
photoreceptors
detect photons of light arriving from the sun or other light source, or reflecting off an object
photon
fundamental unit of electromagnetic radiation
3 layes of the retina
- rods and cones
- Biopolar cells
- Ganglion cells
rods and cones
photoreceptors; deepest against scelera
biopolar cells
interneurons that make synapses with photoreceptors and ganglion cells.
responsible for 30% of input to retinal ganglia and are regulated by amacrine cells
Ganglion cells
send axons out of the eye and into the optic nerve. the shallowest.
Which two groups of retinal cells are transparent?
ganglion and bipolar cells
amacrine cells
interneurons in the retina that are responsible for 70% of input to retinal ganglion
interneurons;
involvled in light adaptation and sensitivity to movement
what regulates bipolar cells in the retina?
amacrine cells
Rods
sensitive to low intensity light
do not discriminate colors
used mostly at night
Cones
require more light for stimulation
detect color
T or F: there are fewer rods than cones in the human retina.
False. more rods than cones.
In rods, the outer segment contains:
pigment
In rods, the inner segment contains:
nucleus & other organelles
also a synaptic terminal filled with neurotransmitter vesicles
Do cones rodes contain axons?
no
What are the two visual pigments?
Retinal & Opsins
Retinal
a chromophore vitamin;
a derivative that absorbs energy from light.
chromophore
color
what Vitamin is required for retinol?
vitamin A